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- W3049453998 abstract "The effects of phorbol esters on phospholipase D activity were studied in C-6 glioma cells. The cell lipids were prelabelled with [ 3 H]-glycerol or [ 14 C]-arachidonic acid. Phosphatidylethanol was formed during stimulation with 100nM 12-0-tetradecanoylphorbol-13-acetate (TPA), when ethanol was present in the culture medium. After 30 minutes of stimulation, phosphatidylethanol constituted 2.6% of the [ 3 H]-glycerol-labelled lipids. Stimulating the cells with TPA in the absence of ethanol caused a significant increase in labelled phosphatidic acid. This increase was inhibited by ethanol. The present findings demonstrate that TPA stimulates phospholipase D activity in cultured C-6 glioma cells." @default.
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- W3049453998 date "1989-03-01" @default.
- W3049453998 modified "2023-09-24" @default.
- W3049453998 title "Phorbol Esters Stimulate Phospholipase D Activity in C-6 Glioma Cells" @default.
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- W3049453998 doi "https://doi.org/10.1177/026119298901600309" @default.
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