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- W3049515335 abstract "Background: By the dawn of this modernera of science, the prime challenge of physician is cardiovascular disease(CVD). The most important modifiable risk factors of CVDs are unhealthy diet,physical inactivity and tobacco use. The effects of unhealthy diet and physicalinactivity include abnormal blood lipid, obesity and hypertension. We tried toevaluate and correlate the pattern of lipid profile in obese and non-obesehypertensive patients. Objectives: This study was conducted at medicinedepartment of Cumilla Medical College Hospital. The principal aim was toevaluate the lipid profile in obese and non-obese adult hypertensive patients. Methodology: During this cross sectional analytical study, a total of 100 adult hypertensivepatients were taken by purposive sampling. Among them 50 (group 1) patientswere taken those were obese and 50 (group 2) patients takenthose were non-obese according to BMI measurement on operational definition.Diagnosis of hypertension would be established with the help of ambulatory BPmeasurements two occasions few minutes apart. The staging of hypertension wasdone according to JNC7 Criteria. Morning blood samples were taken after 8 - 12 hours of fastingand lipid profiles were done on authentic laboratories. The laboratory valueswere interpreted according to the operational definition of dyslipidaemia. Theethical research and review committee approved the study protocol and signedinformed consent was obtained from the participants. The statistics wasanalyzed using the IBM SPSS software of version 19.0. Statistical significancewas set at p Results: Among the two groups, there were 56 (56%)males and 44 (44%) females. The mean age of group 1 (46.10 ± 11.09) wascompared to that of group 2 (45.5 ± 10.6). Lipid profile abnormalities were significantlyhigher in the stage 2 hypertension (59.62%) and stage 3hypertension (66.66%), higher in class 2 obese (100%) and class 3obese subjects (100%), female hypertensive patients had significantly higherBMI than their male counterparts (27.24 ± 3.63 kg/m2 versus29.29 ± 3.99 kg/m2), lipid profiles were higher in the female than male hypertensive patients(63.33% vs 55.35%) but only TC was statistically significant (4.45 ± 1.19 mmol/l versus 4.86 ± 1.29 mmol/l, p (76%) of the obesehypertensive patients had dyslipidaemia whereas 21 (42%) of non-obesehypertensive patients had dyslipidaemia. In multivariate regression, TG wassignificantly and directly associated with BMI of subjects. Dyslipidaemia wasmore prevalent in the age group 30 - 59 of adulthypertensive patients. It showed that obese hypertensive patients hadsignificantly higher SBP (p (p mmol/l versus 4.15 ± 0.57 mmol/l, t = -9.70, p mmol/l versus 2.10 ± 0.45 mmol/l, t = -5.37, p mmol/l versus 2.44 ± 0.53 mmol/l, t = -9.11, p mmol/l versus 1.24 ± 0.57 mmol/l, t = -0.25, p= 0.08)..." @default.
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- W3049515335 date "2020-01-01" @default.
- W3049515335 modified "2023-10-12" @default.
- W3049515335 title "Evaluation of Lipid Profile in Obese and Non-Obese Hypertensive Adult Patients Attended in Medicine Department of a Medical College Hospital of Bangladesh" @default.
- W3049515335 doi "https://doi.org/10.4236/wjcd.2020.108052" @default.
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