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- W3049578589 abstract "Significance Tissue-resident macrophages can arise from multiple origins during embryonic and adult hematopoiesis. They are important cells regulating a wide range of biological processes, such as tissue remodeling during organogenesis, tissue homeostasis in the steady state, tissue repair following injury, and immune response to pathogens. Although the origins and tissue-specific functions of resident macrophages have been extensively studied in many other tissues, they are not well characterized in skeletal muscle. Our study characterized the origins, tissue-specific gene expression, and diverse functions of skeletal muscle-resident macrophages in the steady state. Our findings provide a knowledge base for future studies of the roles of skeletal muscle-resident macrophages in various disease states." @default.
- W3049578589 created "2020-08-21" @default.
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- W3049578589 date "2020-08-13" @default.
- W3049578589 modified "2023-09-30" @default.
- W3049578589 title "Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages" @default.
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- W3049578589 doi "https://doi.org/10.1073/pnas.1915950117" @default.
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