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• W3049761730 endingPage "100832" @default.
• W3049761730 startingPage "100832" @default.
• W3049761730 abstract "Gastric cancer is one of the leading causes of cancer-related deaths globally. Although, understanding the molecular mechanisms leading to gastric carcinogenesis has gained much importance in the last few decades, yet biomarkers for early detection are not available so far. Kashmir valley- India, represents a high-risk cancer region, has unique dietary and sociocultural practices, which makes it an intriguing region for studying the etiology of gastric cancer. Although several studies have been carried out in Kashmir in the recent past to understand the role of genetic and/or environmental factors in the development of the disease, the complete etiology, and causes of the high incidence of this disease, yet remains unclear. This review summarises the currently available results on various dietary, environmental factors, and genetic factors studied in the Kashmiri population and their relevance with the global understanding of the disease. • For early detection of GC, the adoption of modern cancer screening programs in the Asian high-risk regions like Kashmir needs to be formulated. • To understand the molecular underpinning of GC, multicentric collaborative and conclusive studies like GWAS/WES are warranted. • This review summarises currently available results on various dietary, environmental and genetic factors studied in Kashmiri population ." @default.
• W3049761730 created "2020-08-21" @default.
• W3049761730 creator A5032958373 @default.
• W3049761730 creator A5045108036 @default.
• W3049761730 creator A5065693959 @default.
• W3049761730 creator A5074130748 @default.
• W3049761730 date "2020-12-01" @default.
• W3049761730 modified "2023-09-26" @default.
• W3049761730 title "A decade in unravelling the etiology of gastric carcinogenesis in Kashmir, India – A high risk region" @default.
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