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- W305098563 abstract "The objective of this paper was to find out whether the immunosuppression caused by dexamethasone can have an effect on the activation of encephalitozoonosis in experimentally infected mice and, simultaneously, whether Encephalitozoon cuniculi itself has an immunosuppressive effect on the course of this infection. Immunocompetent mice of the ICR line suppressed by dexamethasone (1.6 mg.kg(1)) were infected experimentally with microsporidium E. Cuniculi by intraperitoneal administration of 5 x 10(7) spores. During 42 d of the experiment, the values of differential white blood count, CD4(+) and CD8(+) T-lymphocytes, as well as CD 19(+) B-lymphocytes in blood were observed and recorded. The achieved results point to the fact that E. Cuniculi itself in the early stages of infection leads to a considerable decrease in the number of leukocytes and causes suppression of T-cell immune response. In combination with dexamethasone it also results in the suppression of both T and B-lymphocytes." @default.
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- W305098563 date "2003-01-01" @default.
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- W305098563 title "Immunosuppressive effect of Encephalitozoon cuniculi Full source: Bulletin of the Veterinary Institute in Pulawy, 2003, Vol 47, Iss 1, pp 113-120 Author keywords: mice; Encephalitozoon cuniculi; immunosuppression; T-lymphocytes; B- lymphocytes; experimentation KeyWords Plus: TRANSCRIPTION; INFECTION; INHIBIT TGA/Book No.: 697GJ Discipline: Veterinary Science & Medicine" @default.
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