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- W305190064 abstract "In the period 01. 01. 1984–31. 12. 1995 a total of 317 adult AML patients were diagnosed in the counties of Funen and Ribe, corresponding to an annual incidence rate of 4.8/105. The median age of these patients was 68 years. Curative chemotherapy was administered to 203 patients (64%) with a median age of 62 years. The three consecutive 4-year periods were characterized by somewhat different principles of AML treatment. In the periods 1984–1987 and 1988–1991 most patients received daunorubicin-AraC, and aclarubicin-AraC, respectively, as induction therapy. In both periods three fourths of CR patients received high-dose AraC based post-remission therapy. In the period 1991–1995 almost all patients were treated with repeated courses of mitoxantrone and high-dose AraC. The CR rate increased from 43% to 77% in the study period. The duration of CR did not change over time, whereas a prolongation of survival was seen, indicating that around 20% of all patients with AML can now be cured.KeywordsAcute Myeloid LeukemiaInduction TherapyCytosine ArabinosideAnnual Incidence RateToxic DeathThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W305190064 date "1998-01-01" @default.
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- W305190064 title "Improved Results of AML Treatment in Adults during a 12-Year Period. A Population-Based Study" @default.
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- W305190064 doi "https://doi.org/10.1007/978-3-642-71960-8_118" @default.
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