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- W305824474 abstract "The limit of sensitivity of an oral test for detection of the insulinotropic action of exogenous nutrients was investigated by enteral administration of L-leucine (0.4μmol per g body wt) to overnight fasted conscious male rats and subsequent measurement of both plasma D-glucose and insulin concentrations. Despite the fact that the amount of L-leucine given by gastric tubing represented less than 0.2kcal/kg body wt, it increased the paired ratio between plasma insulin and D-glucose concentrations during the first 30min of the test to a mean level higher than that found in control experiments including the sole administration of H 2 O. This experimental design is thus well suited to assess the insulinotropic capacity of both known or new exogenous nutrients given alone or in combination." @default.
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- W305824474 date "2003-01-01" @default.
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- W305824474 title "Sensitivity of an oral test for detection of the insulinotropic action of exogenous nutrients: experiments with L-leucine" @default.
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