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- W3058275270 abstract "Abstract Methodology is presented for the synthesis of 6α/β-3-dehydroxynaltrexamines and 6α/β-N-methyl-3-dehydroxynaltrexamines. A stereoselective route is provided for each target compound while a novel one-pot method for the synthesis of 6α/β-N-methyl-3-dehydroxynaltrexamines is also explored. These results enable the versatile and efficient preparation of key epoxymorphinan intermediates to facilitate future selective opioid ligand discovery and development." @default.
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- W3058275270 date "2020-09-01" @default.
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- W3058275270 title "Stereoselective syntheses of 3-dehydroxynaltrexamines and N-methyl-3-dehydroxynaltrexamines" @default.
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- W3058275270 doi "https://doi.org/10.1016/j.tetlet.2020.152379" @default.
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