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- W3062505952 abstract "Abstract Investigating the evolution of complex phenotypes and the underlying molecular bases of their variation is critical to understand how organisms adapt to their environment. Applying classical quantitative genetics on a segregating population derived from a Can-0xCol-0 cross, we identify the MADS-box transcription factor FLOWERING LOCUS M (FLM) as a player of the phenotypic variation in plant growth and color. We show that allelic variation at FLM modulates plant growth strategy along the leaf economics spectrum, a trade-off between resource acquisition and resource conservation, observable across thousands of plant species. Functional differences at FLM rely on a single intronic substitution, disturbing transcript splicing and leading to the accumulation of non-functional FLM transcripts. Associations between this substitution and phenotypic and climatic data across Arabidopsis natural populations, show how noncoding genetic variation at a single gene might be adaptive through pleiotropic effects." @default.
- W3062505952 created "2020-08-24" @default.
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- W3062505952 date "2020-08-18" @default.
- W3062505952 modified "2023-10-11" @default.
- W3062505952 title "Natural variation at FLM splicing has pleiotropic effects modulating ecological strategies in Arabidopsis thaliana" @default.
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- W3062505952 doi "https://doi.org/10.1038/s41467-020-17896-w" @default.
- W3062505952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7435183" @default.
- W3062505952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32811829" @default.
- W3062505952 hasPublicationYear "2020" @default.
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