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- W3062807732 endingPage "117594" @default.
- W3062807732 startingPage "117594" @default.
- W3062807732 abstract "This work describes the application of the gyroid model to represent a cryogel structure whose mass and momentum transport were investigated via Computational Fluid Dynamics (CFD) simulations. Initially, a gyroid was built using a computer platform and was morphologically characterized in terms of the tortuosity distribution, porosity and specific surface area. Hydrodynamic characteristics were then obtained, including permeability, pressure drop and Residence Time Distribution (RTD). Analyzing the velocity field, a heterogeneous flow was observed due to curve obstacles. This phenomenon was more noticeable at high flow rates due to lower contraction of the RTD curve which results in undesired conditions for the adsorption process. From a scaling analysis, mass transfer is governed by advection, adsorption and axial dispersion. Finally, there was a close agreement between the experimental and predicted breakthrough for different flow rates, indicating that the gyroid model was adequate to describe the flow, mass transfer and adsorption profile in the cryogel matrix. This is the first time that gyroid architecture is used to portray and simulate a bioseparation process in a cryogel chromatographic column." @default.
- W3062807732 created "2020-08-24" @default.
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- W3062807732 date "2021-01-01" @default.
- W3062807732 modified "2023-10-14" @default.
- W3062807732 title "The potential use of a gyroid structure to represent monolithic matrices for bioseparation purposes: Fluid dynamics and mass transfer analysis via CFD" @default.
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- W3062807732 doi "https://doi.org/10.1016/j.seppur.2020.117594" @default.
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