FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3065972166> ?p ?o ?g. }

• W3065972166 abstract "To evaluate the incidence and types of chromosomal abnormalities in pregnancy loss and aborted fetuses with anomaly and compare the performance of subtelomeric MLPA and chromosomal microarray analysis (CMA) in these specimens.Samples were collected from spontaneous miscarriages, stillbirths and aborted fetuses with anomaly between January 2015 and April 2019. Chromosomal abnormalities were detected using subtelomeric MLPA and CMA.Among the 172 miscarriage samples, CMA detected pathogenic chromosomal abnormalities in 88 cases. MLPA could identified all aneuploidies and most pathogenic CNVs, missing all polyploidies; Of the 30 stillbirths, one pathogenic CNV and two VOUS were identified by CMA, all of which were missed from MLPA; Of the 135 aborted fetuses with anomaly, CMA identified pathogenic chromosomal abnormalities in 32 fetuses (23.7%); 18.95% in fetuses with isolated, and 35% in fetuses with multiple anomalies. MLPA can identify all aneuploidies but missing most pathogenic CNVs.Our systematical comparison of subtelomeric MLPA and CMA for chromosomal analysis of tissue from pregnancy loss and aborted fetuses with anomaly is useful for assessing clinical utility of these techniques. MLPA screening, coupled with CMA analysis, is a cost-effective approach to detect chromosomal abnormalities in miscarriage and anomalous fetuses. However, MLPA might not be appropriate for chromosome analysis in stillbirth without structural anomaly; further research with more samples is needed." @default.
• W3065972166 created "2020-08-24" @default.
• W3065972166 creator A5017941291 @default.
• W3065972166 creator A5018146205 @default.
• W3065972166 creator A5020430191 @default.
• W3065972166 creator A5027293120 @default.
• W3065972166 creator A5030630890 @default.
• W3065972166 creator A5033893376 @default.
• W3065972166 creator A5059052987 @default.
• W3065972166 creator A5059500617 @default.
• W3065972166 creator A5080646928 @default.
• W3065972166 date "2020-08-18" @default.
• W3065972166 modified "2023-10-16" @default.
• W3065972166 title "Analysis of tissue from pregnancy loss and aborted fetus with ultrasound anomaly using subtelomeric MLPA and chromosomal array analysis" @default.
• W3065972166 cites W1538732295 @default.
• W3065972166 cites W1985885015 @default.
• W3065972166 cites W2003063028 @default.
• W3065972166 cites W2003538821 @default.
• W3065972166 cites W2023532519 @default.
• W3065972166 cites W2025471108 @default.
• W3065972166 cites W2040034581 @default.
• W3065972166 cites W2071549738 @default.
• W3065972166 cites W2073005651 @default.
• W3065972166 cites W2131144811 @default.
• W3065972166 cites W2144967747 @default.
• W3065972166 cites W2378730462 @default.
• W3065972166 cites W2407466130 @default.
• W3065972166 cites W2496405735 @default.
• W3065972166 cites W2509663081 @default.
• W3065972166 cites W2554798922 @default.
• W3065972166 cites W2594530966 @default.
• W3065972166 cites W2621037244 @default.
• W3065972166 cites W2766691075 @default.
• W3065972166 cites W2797817786 @default.
• W3065972166 cites W2894833808 @default.
• W3065972166 cites W2922161539 @default.
• W3065972166 cites W2938613811 @default.
• W3065972166 cites W4211211389 @default.
• W3065972166 doi "https://doi.org/10.1080/14767058.2020.1808612" @default.
• W3065972166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32811234" @default.
• W3065972166 hasPublicationYear "2020" @default.
• W3065972166 type Work @default.
• W3065972166 sameAs 3065972166 @default.
• W3065972166 citedByCount "1" @default.
• W3065972166 countsByYear W30659721662020 @default.
• W3065972166 crossrefType "journal-article" @default.
• W3065972166 hasAuthorship W3065972166A5017941291 @default.
• W3065972166 hasAuthorship W3065972166A5018146205 @default.
• W3065972166 hasAuthorship W3065972166A5020430191 @default.
• W3065972166 hasAuthorship W3065972166A5027293120 @default.
• W3065972166 hasAuthorship W3065972166A5030630890 @default.
• W3065972166 hasAuthorship W3065972166A5033893376 @default.
• W3065972166 hasAuthorship W3065972166A5059052987 @default.
• W3065972166 hasAuthorship W3065972166A5059500617 @default.
• W3065972166 hasAuthorship W3065972166A5080646928 @default.
• W3065972166 hasConcept C104317684 @default.
• W3065972166 hasConcept C120599132 @default.
• W3065972166 hasConcept C120821319 @default.
• W3065972166 hasConcept C131872663 @default.
• W3065972166 hasConcept C141231307 @default.
• W3065972166 hasConcept C172680121 @default.
• W3065972166 hasConcept C23069440 @default.
• W3065972166 hasConcept C2779234561 @default.
• W3065972166 hasConcept C2779245376 @default.
• W3065972166 hasConcept C30481170 @default.
• W3065972166 hasConcept C36823959 @default.
• W3065972166 hasConcept C54355233 @default.
• W3065972166 hasConcept C71924100 @default.
• W3065972166 hasConcept C86803240 @default.
• W3065972166 hasConceptScore W3065972166C104317684 @default.
• W3065972166 hasConceptScore W3065972166C120599132 @default.
• W3065972166 hasConceptScore W3065972166C120821319 @default.
• W3065972166 hasConceptScore W3065972166C131872663 @default.
• W3065972166 hasConceptScore W3065972166C141231307 @default.
• W3065972166 hasConceptScore W3065972166C172680121 @default.
• W3065972166 hasConceptScore W3065972166C23069440 @default.
• W3065972166 hasConceptScore W3065972166C2779234561 @default.
• W3065972166 hasConceptScore W3065972166C2779245376 @default.
• W3065972166 hasConceptScore W3065972166C30481170 @default.
• W3065972166 hasConceptScore W3065972166C36823959 @default.
• W3065972166 hasConceptScore W3065972166C54355233 @default.
• W3065972166 hasConceptScore W3065972166C71924100 @default.
• W3065972166 hasConceptScore W3065972166C86803240 @default.
• W3065972166 hasLocation W30659721661 @default.
• W3065972166 hasLocation W30659721662 @default.
• W3065972166 hasOpenAccess W3065972166 @default.
• W3065972166 hasPrimaryLocation W30659721661 @default.
• W3065972166 hasRelatedWork W1046288 @default.
• W3065972166 hasRelatedWork W1097654 @default.
• W3065972166 hasRelatedWork W11399465 @default.
• W3065972166 hasRelatedWork W14201379 @default.
• W3065972166 hasRelatedWork W1424066 @default.
• W3065972166 hasRelatedWork W15070423 @default.
• W3065972166 hasRelatedWork W2277998 @default.
• W3065972166 hasRelatedWork W2784653 @default.
• W3065972166 hasRelatedWork W8597326 @default.
• W3065972166 hasRelatedWork W925691 @default.
• W3065972166 isParatext "false" @default.
• W3065972166 isRetracted "false" @default.
• W3065972166 magId "3065972166" @default.

• next