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• W3067209413 endingPage "223" @default.
• W3067209413 startingPage "207" @default.
• W3067209413 abstract "T cells are an essential component of the immune system that provide antigen-specific acute and long lasting immune responses to infections and tumors, ascertain the maintenance of immunological tolerance and, on the flipside, mediate autoimmunity in a variety of diseases. The activation of T cells through antigen recognition by the T cell receptor (TCR) results in transient and sustained Ca2+ signals that are shaped by the opening of Ca2+ channels in the plasma membrane and cellular organelles. The dynamic regulation of intracellular Ca2+ concentrations controls a variety of T cell functions on the timescale of seconds to days after signal initiation. Among the more recently identified roles of Ca2+ signaling in T cells is the regulation of metabolic pathways that control the function of many T cell subsets. In this review, we discuss how Ca2+ regulates several metabolic programs in T cells such as the activation of AMPK and the PI3K-AKT-mTORC1 pathway, aerobic glycolysis, mitochondrial metabolism including tricarboxylic acid (TCA) cycle function and oxidative phosphorylation (OXPHOS), as well as lipid metabolism." @default.
• W3067209413 created "2020-08-24" @default.
• W3067209413 creator A5056967422 @default.
• W3067209413 creator A5063614514 @default.
• W3067209413 creator A5077890752 @default.
• W3067209413 creator A5091404565 @default.
• W3067209413 date "2020-10-01" @default.
• W3067209413 modified "2023-10-06" @default.
• W3067209413 title "Calcium regulation of T cell metabolism" @default.
• W3067209413 cites W1165140024 @default.
• W3067209413 cites W1496297920 @default.
• W3067209413 cites W1555531912 @default.
• W3067209413 cites W1597438451 @default.
• W3067209413 cites W1756031092 @default.
• W3067209413 cites W181688216 @default.
• W3067209413 cites W1826298574 @default.
• W3067209413 cites W1844259691 @default.
• W3067209413 cites W1882193637 @default.
• W3067209413 cites W1917241220 @default.
• W3067209413 cites W1934528477 @default.
• W3067209413 cites W1935830997 @default.
• W3067209413 cites W1964005617 @default.
• W3067209413 cites W1965671023 @default.
• W3067209413 cites W1967727543 @default.
• W3067209413 cites W1967799970 @default.
• W3067209413 cites W1970041220 @default.
• W3067209413 cites W1974744093 @default.
• W3067209413 cites W1975566288 @default.
• W3067209413 cites W1976714959 @default.
• W3067209413 cites W1977748495 @default.
• W3067209413 cites W1978096280 @default.
• W3067209413 cites W1986213783 @default.
• W3067209413 cites W1986457087 @default.
• W3067209413 cites W1988042264 @default.
• W3067209413 cites W1988248740 @default.
• W3067209413 cites W1988751970 @default.
• W3067209413 cites W1990278643 @default.
• W3067209413 cites W1992250154 @default.
• W3067209413 cites W1992678387 @default.
• W3067209413 cites W1993023349 @default.
• W3067209413 cites W1994252478 @default.
• W3067209413 cites W1996021619 @default.
• W3067209413 cites W1999324987 @default.
• W3067209413 cites W2001568034 @default.
• W3067209413 cites W2003258557 @default.
• W3067209413 cites W2003398132 @default.
• W3067209413 cites W2005299533 @default.
• W3067209413 cites W2006441888 @default.
• W3067209413 cites W2008659179 @default.
• W3067209413 cites W2015798899 @default.
• W3067209413 cites W2016752484 @default.
• W3067209413 cites W2019023589 @default.
• W3067209413 cites W2040891426 @default.
• W3067209413 cites W2043054174 @default.
• W3067209413 cites W2053444468 @default.
• W3067209413 cites W2054772081 @default.
• W3067209413 cites W2057635215 @default.
• W3067209413 cites W2063888187 @default.
• W3067209413 cites W2064250340 @default.
• W3067209413 cites W2067841051 @default.
• W3067209413 cites W2068048197 @default.
• W3067209413 cites W2070776182 @default.
• W3067209413 cites W2070805734 @default.
• W3067209413 cites W2072240385 @default.
• W3067209413 cites W2085584630 @default.
• W3067209413 cites W2090120422 @default.
• W3067209413 cites W2091380103 @default.
• W3067209413 cites W2092340487 @default.
• W3067209413 cites W2092608998 @default.
• W3067209413 cites W2094430434 @default.
• W3067209413 cites W2097439505 @default.
• W3067209413 cites W2098465830 @default.
• W3067209413 cites W2102216850 @default.
• W3067209413 cites W2109596491 @default.
• W3067209413 cites W2115021528 @default.
• W3067209413 cites W2116676186 @default.
• W3067209413 cites W2120506165 @default.
• W3067209413 cites W2121711825 @default.
• W3067209413 cites W2123489236 @default.
• W3067209413 cites W2133002620 @default.
• W3067209413 cites W2133204871 @default.
• W3067209413 cites W2138760035 @default.
• W3067209413 cites W2143319221 @default.
• W3067209413 cites W2145177312 @default.
• W3067209413 cites W2146664668 @default.
• W3067209413 cites W2146791037 @default.
• W3067209413 cites W2157579772 @default.
• W3067209413 cites W2157739158 @default.
• W3067209413 cites W2159903725 @default.
• W3067209413 cites W2160551785 @default.
• W3067209413 cites W2161210718 @default.
• W3067209413 cites W2162927138 @default.
• W3067209413 cites W2166044246 @default.
• W3067209413 cites W2167378780 @default.
• W3067209413 cites W2167432954 @default.
• W3067209413 cites W2200383735 @default.
• W3067209413 cites W2229423562 @default.
• W3067209413 cites W2261313271 @default.

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