FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3068045994> ?p ?o ?g. }

• W3068045994 endingPage "2179" @default.
• W3068045994 startingPage "2171" @default.
• W3068045994 abstract "Studies of cancer risk among relatives of children with cancer beyond parents and siblings are limited. We have investigated the cancer risk up to the third degree of relation in families with pediatric cancer to reveal patterns of inheritance.A single-center cohort of 757 patients with pediatric cancer was linked to the Swedish National Population Register, resulting in 16,137 relatives up to the third degree of relation. All relatives were matched to the Swedish Cancer Register, and standard incidence ratios (SIR) were calculated to define relatives at risk.Children and adults up to the third degree of relation had increased cancer risk, with SIRs of 1.48 (P = 0.01) and 1.07 (P < 0.01), respectively. The SIRs for first- and third-degree adult relatives were 1.22 and 1.10, respectively, but no increased risk was observed in second-degree relatives. Male relatives had a higher risk than females, especially when related to a girl and when the child had leukemia. The risk was mainly increased for lung, prostate, and gastrointestinal cancer. When excluding 29 families of children with known pathogenic germline variants, the increased risk remained.Relatives to children with cancer up to third degree of relation have an increased cancer risk. Known pathogenic germline variants do not explain this increased risk.The overall increased cancer risk among relatives of children with cancer in this population-based cohort strengthens the importance of surveillance programs for families with pediatric cancer." @default.
• W3068045994 created "2020-08-24" @default.
• W3068045994 creator A5002339556 @default.
• W3068045994 creator A5018984128 @default.
• W3068045994 creator A5054216397 @default.
• W3068045994 creator A5057166573 @default.
• W3068045994 creator A5057281435 @default.
• W3068045994 creator A5060286246 @default.
• W3068045994 creator A5081056640 @default.
• W3068045994 creator A5090162606 @default.
• W3068045994 date "2020-11-01" @default.
• W3068045994 modified "2023-10-16" @default.
• W3068045994 title "Increased Cancer Risk in Families with Pediatric Cancer Is Associated with Gender, Age, Diagnosis, and Degree of Relation to the Child" @default.
• W3068045994 cites W1526999808 @default.
• W3068045994 cites W1856250135 @default.
• W3068045994 cites W1911918948 @default.
• W3068045994 cites W1947479376 @default.
• W3068045994 cites W1970001421 @default.
• W3068045994 cites W1976707160 @default.
• W3068045994 cites W1983318227 @default.
• W3068045994 cites W2000329919 @default.
• W3068045994 cites W2012430676 @default.
• W3068045994 cites W2023720191 @default.
• W3068045994 cites W2029186878 @default.
• W3068045994 cites W2043201460 @default.
• W3068045994 cites W2044702888 @default.
• W3068045994 cites W2048973370 @default.
• W3068045994 cites W2069411394 @default.
• W3068045994 cites W2076830625 @default.
• W3068045994 cites W2078339337 @default.
• W3068045994 cites W2082144926 @default.
• W3068045994 cites W2087025655 @default.
• W3068045994 cites W2089155477 @default.
• W3068045994 cites W2096393244 @default.
• W3068045994 cites W2146167921 @default.
• W3068045994 cites W2170322051 @default.
• W3068045994 cites W2170958906 @default.
• W3068045994 cites W2272820807 @default.
• W3068045994 cites W2303408208 @default.
• W3068045994 cites W2324822457 @default.
• W3068045994 cites W2778047716 @default.
• W3068045994 cites W2789869568 @default.
• W3068045994 cites W2790866095 @default.
• W3068045994 cites W2799574682 @default.
• W3068045994 cites W2899197098 @default.
• W3068045994 cites W3003148756 @default.
• W3068045994 cites W2003915294 @default.
• W3068045994 doi "https://doi.org/10.1158/1055-9965.epi-20-0322" @default.
• W3068045994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32856606" @default.
• W3068045994 hasPublicationYear "2020" @default.
• W3068045994 type Work @default.
• W3068045994 sameAs 3068045994 @default.
• W3068045994 citedByCount "2" @default.
• W3068045994 countsByYear W30680459942021 @default.
• W3068045994 countsByYear W30680459942023 @default.
• W3068045994 crossrefType "journal-article" @default.
• W3068045994 hasAuthorship W3068045994A5002339556 @default.
• W3068045994 hasAuthorship W3068045994A5018984128 @default.
• W3068045994 hasAuthorship W3068045994A5054216397 @default.
• W3068045994 hasAuthorship W3068045994A5057166573 @default.
• W3068045994 hasAuthorship W3068045994A5057281435 @default.
• W3068045994 hasAuthorship W3068045994A5060286246 @default.
• W3068045994 hasAuthorship W3068045994A5081056640 @default.
• W3068045994 hasAuthorship W3068045994A5090162606 @default.
• W3068045994 hasBestOaLocation W30680459941 @default.
• W3068045994 hasConcept C120665830 @default.
• W3068045994 hasConcept C121332964 @default.
• W3068045994 hasConcept C121608353 @default.
• W3068045994 hasConcept C126322002 @default.
• W3068045994 hasConcept C143998085 @default.
• W3068045994 hasConcept C144024400 @default.
• W3068045994 hasConcept C149923435 @default.
• W3068045994 hasConcept C187212893 @default.
• W3068045994 hasConcept C2776256026 @default.
• W3068045994 hasConcept C2779862289 @default.
• W3068045994 hasConcept C2781179581 @default.
• W3068045994 hasConcept C2908647359 @default.
• W3068045994 hasConcept C50440223 @default.
• W3068045994 hasConcept C61511704 @default.
• W3068045994 hasConcept C71924100 @default.
• W3068045994 hasConcept C72563966 @default.
• W3068045994 hasConcept C99454951 @default.
• W3068045994 hasConceptScore W3068045994C120665830 @default.
• W3068045994 hasConceptScore W3068045994C121332964 @default.
• W3068045994 hasConceptScore W3068045994C121608353 @default.
• W3068045994 hasConceptScore W3068045994C126322002 @default.
• W3068045994 hasConceptScore W3068045994C143998085 @default.
• W3068045994 hasConceptScore W3068045994C144024400 @default.
• W3068045994 hasConceptScore W3068045994C149923435 @default.
• W3068045994 hasConceptScore W3068045994C187212893 @default.
• W3068045994 hasConceptScore W3068045994C2776256026 @default.
• W3068045994 hasConceptScore W3068045994C2779862289 @default.
• W3068045994 hasConceptScore W3068045994C2781179581 @default.
• W3068045994 hasConceptScore W3068045994C2908647359 @default.
• W3068045994 hasConceptScore W3068045994C50440223 @default.
• W3068045994 hasConceptScore W3068045994C61511704 @default.
• W3068045994 hasConceptScore W3068045994C71924100 @default.
• W3068045994 hasConceptScore W3068045994C72563966 @default.

• next