FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3071121401> ?p ?o ?g. }

• W3071121401 endingPage "22" @default.
• W3071121401 startingPage "1" @default.
• W3071121401 abstract "The purpose of this paper is to review the literature on the impact of antidepressants on depressive symptom severity, quality of life (QoL), morbidity, and mortality in patients with heart failure (HF).Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Reporting Items for Systematic Reviews and Meta-Analyses guidelines, studies published from December 1969 to December 2019 that pertain to depression and HF were identified through the use of the PubMed and PsycINFO databases, using the keywords: 'antidepressant*' and 'heart failure.' Two authors independently conducted a focused analysis and reached a final consensus on 17 studies that met the specific selection criteria and passed the study quality checks.Studies varied in types of antidepressants used as well as in study designs. Ten studies were analyzed for the impact of antidepressant medications on depressive symptom severity. Five of these were randomized controlled trials (RCTs), out of which sertraline and paroxetine showed a significant reduction in depressive symptoms despite the small samples utilized. Four of the 17 studies addressed QoL as part of their outcomes showing no difference for escitalopram (RCT), significantly greater improvements for paroxetine controlled release (RCT), statistical significance for sertraline compared to control (pilot study), and showing significant improvement before and after treatment (open-label trial) for nefazodone. Thirteen of the 17 studies included measures of morbidity and mortality. Although early analyses have pointed to an association of antidepressant use and mortality particularly with fluoxetine, the reviewed studies showed no increase in mortality for antidepressants, and secondary analyses showed improved mortality in patients who achieved remission of depressive symptoms.Out of the various antidepressants studied, which included sertraline, paroxetine, escitalopram, citalopram, bupropion, nefazodone, and nortriptyline, selective serotonin reuptake inhibitors seem to be a safe treatment option for patients with depression and HF. However, due to the variety of study designs as well as the mixed results for each antidepressant, more information for reducing depression severity, morbidity, and mortality and improving quality of life in patients with HF should be examined using robust large sample RCTs." @default.
• W3071121401 created "2020-08-24" @default.
• W3071121401 date "2020-07-29" @default.
• W3071121401 modified "2023-10-14" @default.
• W3071121401 title "The impact of antidepressants on depressive symptom severity, quality of life, morbidity, and mortality in heart failure: a systematic review" @default.
• W3071121401 cites W1268568596 @default.
• W3071121401 cites W1608367062 @default.
• W3071121401 cites W1967653075 @default.
• W3071121401 cites W1981168183 @default.
• W3071121401 cites W1984979845 @default.
• W3071121401 cites W2006879280 @default.
• W3071121401 cites W2010336512 @default.
• W3071121401 cites W2013828020 @default.
• W3071121401 cites W2029552522 @default.
• W3071121401 cites W2032820199 @default.
• W3071121401 cites W2041298018 @default.
• W3071121401 cites W2042702410 @default.
• W3071121401 cites W2044276242 @default.
• W3071121401 cites W2063796565 @default.
• W3071121401 cites W2067934026 @default.
• W3071121401 cites W2079902385 @default.
• W3071121401 cites W2103872936 @default.
• W3071121401 cites W2105437438 @default.
• W3071121401 cites W2113237951 @default.
• W3071121401 cites W2116814036 @default.
• W3071121401 cites W2127129107 @default.
• W3071121401 cites W2136168926 @default.
• W3071121401 cites W2138101557 @default.
• W3071121401 cites W2140804331 @default.
• W3071121401 cites W2141625451 @default.
• W3071121401 cites W2142681986 @default.
• W3071121401 cites W2147735030 @default.
• W3071121401 cites W2153759497 @default.
• W3071121401 cites W2154187447 @default.
• W3071121401 cites W2156098321 @default.
• W3071121401 cites W2158777428 @default.
• W3071121401 cites W2165104304 @default.
• W3071121401 cites W2167651027 @default.
• W3071121401 cites W2199554510 @default.
• W3071121401 cites W2263494736 @default.
• W3071121401 cites W2321873730 @default.
• W3071121401 cites W2403023177 @default.
• W3071121401 cites W2413366946 @default.
• W3071121401 cites W2461819329 @default.
• W3071121401 cites W246286872 @default.
• W3071121401 cites W2467869403 @default.
• W3071121401 cites W2502560620 @default.
• W3071121401 cites W2605671917 @default.
• W3071121401 cites W2605951313 @default.
• W3071121401 cites W2627134445 @default.
• W3071121401 cites W2737551789 @default.
• W3071121401 cites W2770575748 @default.
• W3071121401 cites W2793543393 @default.
• W3071121401 cites W2808520827 @default.
• W3071121401 cites W2974351413 @default.
• W3071121401 doi "https://doi.org/10.7573/dic.2020-5-4" @default.
• W3071121401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7398616" @default.
• W3071121401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32788920" @default.
• W3071121401 hasPublicationYear "2020" @default.
• W3071121401 type Work @default.
• W3071121401 sameAs 3071121401 @default.
• W3071121401 citedByCount "4" @default.
• W3071121401 countsByYear W30711214012022 @default.
• W3071121401 countsByYear W30711214012023 @default.
• W3071121401 crossrefType "journal-article" @default.
• W3071121401 hasBestOaLocation W30711214011 @default.
• W3071121401 hasConcept C118552586 @default.
• W3071121401 hasConcept C126322002 @default.
• W3071121401 hasConcept C139719470 @default.
• W3071121401 hasConcept C142724271 @default.
• W3071121401 hasConcept C159110408 @default.
• W3071121401 hasConcept C162324750 @default.
• W3071121401 hasConcept C168563851 @default.
• W3071121401 hasConcept C170493617 @default.
• W3071121401 hasConcept C17744445 @default.
• W3071121401 hasConcept C189708586 @default.
• W3071121401 hasConcept C199539241 @default.
• W3071121401 hasConcept C2775864247 @default.
• W3071121401 hasConcept C2776134451 @default.
• W3071121401 hasConcept C2776867660 @default.
• W3071121401 hasConcept C2777490545 @default.
• W3071121401 hasConcept C2777669559 @default.
• W3071121401 hasConcept C2777828372 @default.
• W3071121401 hasConcept C2777843972 @default.
• W3071121401 hasConcept C2779177272 @default.
• W3071121401 hasConcept C2779419675 @default.
• W3071121401 hasConcept C2779473830 @default.
• W3071121401 hasConcept C2779583969 @default.
• W3071121401 hasConcept C2779908668 @default.
• W3071121401 hasConcept C2779951463 @default.
• W3071121401 hasConcept C558461103 @default.
• W3071121401 hasConcept C71924100 @default.
• W3071121401 hasConcept C95190672 @default.
• W3071121401 hasConceptScore W3071121401C118552586 @default.
• W3071121401 hasConceptScore W3071121401C126322002 @default.
• W3071121401 hasConceptScore W3071121401C139719470 @default.
• W3071121401 hasConceptScore W3071121401C142724271 @default.
• W3071121401 hasConceptScore W3071121401C159110408 @default.

• next