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• W3072303676 abstract "Abstract Background Members of the bacterial family Flavobacteriaceae are widely distributed in the marine environment and often found associated with algae, fish, detritus or marine invertebrates. Yet, little is known about the characteristics that drive their ubiquity in diverse ecological niches. Here, we provide an overview of functional traits common to taxonomically diverse members of the family Flavobacteriaceae from different environmental sources, with a focus on the Marine clade. We include seven newly sequenced marine sponge-derived strains that were also tested for gliding motility and antimicrobial activity. Results Comparative genomics revealed that genome similarities appeared to be correlated to 16S rRNA gene- and genome-based phylogeny, while differences were mostly associated with nutrient acquisition, such as carbohydrate metabolism and gliding motility. The high frequency and diversity of genes encoding polymer-degrading enzymes, often arranged in polysaccharide utilization loci (PULs), support the capacity of marine Flavobacteriaceae to utilize diverse carbon sources. Homologs of gliding proteins were widespread among all studied Flavobacteriaceae in contrast to members of other phyla, highlighting the particular presence of this feature within the Bacteroidetes . Notably, not all bacteria predicted to glide formed spreading colonies. Genome mining uncovered a diverse secondary metabolite biosynthesis arsenal of Flavobacteriaceae with high prevalence of gene clusters encoding pathways for the production of antimicrobial, antioxidant and cytotoxic compounds. Antimicrobial activity tests showed, however, that the phenotype differed from the genome-derived predictions for the seven tested strains. Conclusions Our study elucidates the functional repertoire of marine Flavobacteriaceae and highlights the need to combine genomic and experimental data while using the appropriate stimuli to unlock their uncharted metabolic potential." @default.
• W3072303676 created "2020-08-24" @default.
• W3072303676 creator A5014550471 @default.
• W3072303676 creator A5027532801 @default.
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• W3072303676 creator A5030019698 @default.
• W3072303676 creator A5039631392 @default.
• W3072303676 creator A5040359679 @default.
• W3072303676 creator A5043886087 @default.
• W3072303676 creator A5068718584 @default.
• W3072303676 date "2020-08-20" @default.
• W3072303676 modified "2023-10-10" @default.
• W3072303676 title "Comparative genomic analysis of Flavobacteriaceae: insights into carbohydrate metabolism, gliding motility and secondary metabolite biosynthesis" @default.
• W3072303676 cites W1202680985 @default.
• W3072303676 cites W1722029454 @default.
• W3072303676 cites W1807203802 @default.
• W3072303676 cites W1827213771 @default.
• W3072303676 cites W1849874345 @default.
• W3072303676 cites W1886122999 @default.
• W3072303676 cites W1964516944 @default.
• W3072303676 cites W1966138546 @default.
• W3072303676 cites W1966998969 @default.
• W3072303676 cites W1975090911 @default.
• W3072303676 cites W1977852030 @default.
• W3072303676 cites W1982855075 @default.
• W3072303676 cites W1984225141 @default.
• W3072303676 cites W1985609109 @default.
• W3072303676 cites W1987818327 @default.
• W3072303676 cites W1999778012 @default.
• W3072303676 cites W2000277994 @default.
• W3072303676 cites W2008264573 @default.
• W3072303676 cites W2011414219 @default.
• W3072303676 cites W2012671673 @default.
• W3072303676 cites W2015095789 @default.
• W3072303676 cites W2025757392 @default.
• W3072303676 cites W2026181218 @default.
• W3072303676 cites W2026347365 @default.
• W3072303676 cites W2028062032 @default.
• W3072303676 cites W2028479782 @default.
• W3072303676 cites W2028911325 @default.
• W3072303676 cites W2028935316 @default.
• W3072303676 cites W2031611770 @default.
• W3072303676 cites W2038326344 @default.
• W3072303676 cites W2040845548 @default.
• W3072303676 cites W2046305392 @default.
• W3072303676 cites W2055043387 @default.
• W3072303676 cites W2056279562 @default.
• W3072303676 cites W2058311489 @default.
• W3072303676 cites W2063563175 @default.
• W3072303676 cites W2069163869 @default.
• W3072303676 cites W2073073672 @default.
• W3072303676 cites W2076505039 @default.
• W3072303676 cites W2077601582 @default.
• W3072303676 cites W2080746212 @default.
• W3072303676 cites W2081805738 @default.
• W3072303676 cites W2088632292 @default.
• W3072303676 cites W2093078900 @default.
• W3072303676 cites W2096093282 @default.
• W3072303676 cites W2097159477 @default.
• W3072303676 cites W2104677379 @default.
• W3072303676 cites W2105511400 @default.
• W3072303676 cites W2107772251 @default.
• W3072303676 cites W2108234281 @default.
• W3072303676 cites W2110363791 @default.
• W3072303676 cites W2111955985 @default.
• W3072303676 cites W2112364185 @default.
• W3072303676 cites W2114392707 @default.
• W3072303676 cites W2120872367 @default.
• W3072303676 cites W2120902911 @default.
• W3072303676 cites W2122446900 @default.
• W3072303676 cites W2122559203 @default.
• W3072303676 cites W2127175247 @default.
• W3072303676 cites W2127847431 @default.
• W3072303676 cites W2129906608 @default.
• W3072303676 cites W2130597362 @default.
• W3072303676 cites W2131271579 @default.
• W3072303676 cites W2133966658 @default.
• W3072303676 cites W2136264360 @default.
• W3072303676 cites W2136430672 @default.
• W3072303676 cites W2136931384 @default.
• W3072303676 cites W2138874839 @default.
• W3072303676 cites W2149560398 @default.
• W3072303676 cites W2152682668 @default.
• W3072303676 cites W2155806125 @default.
• W3072303676 cites W2158818228 @default.
• W3072303676 cites W2159276044 @default.
• W3072303676 cites W2163908224 @default.
• W3072303676 cites W2166206257 @default.
• W3072303676 cites W2167475108 @default.
• W3072303676 cites W2169267799 @default.
• W3072303676 cites W2169598841 @default.
• W3072303676 cites W2170551349 @default.
• W3072303676 cites W2171165413 @default.
• W3072303676 cites W2187341651 @default.
• W3072303676 cites W2196549304 @default.
• W3072303676 cites W2314006915 @default.
• W3072303676 cites W2315060942 @default.
• W3072303676 cites W2322918442 @default.
• W3072303676 cites W2326830576 @default.
• W3072303676 cites W2330764053 @default.

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