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- W307242022 abstract "This chapter discusses the principles of neural organization. Neuroanatomy is characterized by an explosive development of techniques. The application of modern retrograde labeling techniques, especially the uptake by nerve endings of horseradish peroxidase (HRP) have shown increasingly that one has greatly underestimated, even in the spinal cord, the length, variety, and distribution of intersegmental connections to different target structures. This is more evident for the neurons of the upper part of the central core of the neuraxis, the lower brainstem, which include anything from hypothalamus, and parts of the upper brainstem nuclei down to the medulla oblongata, where the ascending branches of the same neurons may extend as far up as the cerebral cortex and as far down as the spinal cord. This principle may apply particularly to certain specific neuron types—the catecholaminergic or more generally the monoaminergic neuron systems. The building block principle is apparent already at the macroscopic level, its most generally known examples being the segmental organization of the neuraxis. The most elegant and only relatively discovered cases are the assembly of the cerebellum, including both afferent and efferent connections in sagittally oriented relatively narrow disks, and the thalamo-cortical projection principle." @default.
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- W307242022 date "1981-01-01" @default.
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- W307242022 title "PRINCIPLES OF NEURAL ORGANIZATION" @default.
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- W307242022 doi "https://doi.org/10.1016/b978-0-08-026814-9.50006-5" @default.
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