FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3074772937> ?p ?o ?g. }

• W3074772937 endingPage "383.e2" @default.
• W3074772937 startingPage "377" @default.
• W3074772937 abstract "Context Advanced gynecologic malignancies can cause significant vaginal bleeding. Radiotherapy (RT) is often used to palliate symptoms, but limited data exist concerning the optimal dose and expected time to bleeding hemostasis in this population. Objectives 1) To investigate the overall hemostasis response and kinetics of hemostasis in women with gynecologic malignancies receiving palliative RT. 2) To compare the efficacy of short-course RT (SCRT, less than or equal to five fractions, >3.5 Gy per fraction) vs. conventionally fractionated long-course regimens (greater than five fractions). Methods We identified women receiving palliative RT for bleeding gynecologic malignancies. Initial and maximal hemostasis responses (IHR and MHR) were recorded and categorized as progressive bleeding (PD), stable disease (SD), partial response (PR), or complete response (CR). Clinical variables were correlated with response or toxicity using binary logistic regression statistical methods. Results Thirty-three women (median age 63) were identified between 2010 and 2019. Median follow-up and survival after RT were 131 days. About 54.5% (18 of 33) received SCRT. Median time to IHR was five days (two-and-a-half days with SCRT) and 78.8% (26 of 33) responded during treatment. Median time to MHR was 13 days. About 100% achieved PR or CR at MHR. Rates of CR were similar between SCRT (83%) and conventionally fractionated schedules (87%). Average durability of hemostatic control was 5.4 months. Overall rate of rebleeding and Grade 3+ toxicity was 9.1% (3 of 33 each). Conclusion Women receiving SCRT for bleeding gynecologic malignancies achieved rapid symptom control (often during treatment) with minimal rebleeding. In a population whose median survival is four months, SCRT effectively addresses symptomatic disease while minimizing patient burden and toxicity." @default.
• W3074772937 created "2020-08-24" @default.
• W3074772937 creator A5013007800 @default.
• W3074772937 creator A5015054115 @default.
• W3074772937 creator A5026950248 @default.
• W3074772937 creator A5036514898 @default.
• W3074772937 creator A5046322160 @default.
• W3074772937 creator A5070444608 @default.
• W3074772937 creator A5077114810 @default.
• W3074772937 creator A5087620078 @default.
• W3074772937 date "2021-02-01" @default.
• W3074772937 modified "2023-10-18" @default.
• W3074772937 title "A Retrospective Study of Rapid Symptom Response in Bleeding Gynecologic Malignancies With Short Course Palliative Radiation Therapy: Less is More" @default.
• W3074772937 cites W1967038049 @default.
• W3074772937 cites W1970503407 @default.
• W3074772937 cites W1975929167 @default.
• W3074772937 cites W1978343455 @default.
• W3074772937 cites W1997874428 @default.
• W3074772937 cites W2003865781 @default.
• W3074772937 cites W2019403691 @default.
• W3074772937 cites W2031112188 @default.
• W3074772937 cites W2052947296 @default.
• W3074772937 cites W2073511473 @default.
• W3074772937 cites W2077210792 @default.
• W3074772937 cites W2081778499 @default.
• W3074772937 cites W2117437839 @default.
• W3074772937 cites W2118307358 @default.
• W3074772937 cites W2129299671 @default.
• W3074772937 cites W2133116306 @default.
• W3074772937 cites W2142660070 @default.
• W3074772937 cites W2145374260 @default.
• W3074772937 cites W2730486430 @default.
• W3074772937 cites W2900938474 @default.
• W3074772937 cites W2910904219 @default.
• W3074772937 cites W4244503053 @default.
• W3074772937 doi "https://doi.org/10.1016/j.jpainsymman.2020.08.011" @default.
• W3074772937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32822754" @default.
• W3074772937 hasPublicationYear "2021" @default.
• W3074772937 type Work @default.
• W3074772937 sameAs 3074772937 @default.
• W3074772937 citedByCount "4" @default.
• W3074772937 countsByYear W30747729372021 @default.
• W3074772937 countsByYear W30747729372022 @default.
• W3074772937 crossrefType "journal-article" @default.
• W3074772937 hasAuthorship W3074772937A5013007800 @default.
• W3074772937 hasAuthorship W3074772937A5015054115 @default.
• W3074772937 hasAuthorship W3074772937A5026950248 @default.
• W3074772937 hasAuthorship W3074772937A5036514898 @default.
• W3074772937 hasAuthorship W3074772937A5046322160 @default.
• W3074772937 hasAuthorship W3074772937A5070444608 @default.
• W3074772937 hasAuthorship W3074772937A5077114810 @default.
• W3074772937 hasAuthorship W3074772937A5087620078 @default.
• W3074772937 hasConcept C126322002 @default.
• W3074772937 hasConcept C141071460 @default.
• W3074772937 hasConcept C151730666 @default.
• W3074772937 hasConcept C159110408 @default.
• W3074772937 hasConcept C167135981 @default.
• W3074772937 hasConcept C2778589496 @default.
• W3074772937 hasConcept C2779343474 @default.
• W3074772937 hasConcept C2908647359 @default.
• W3074772937 hasConcept C2994186709 @default.
• W3074772937 hasConcept C509974204 @default.
• W3074772937 hasConcept C71924100 @default.
• W3074772937 hasConcept C86803240 @default.
• W3074772937 hasConcept C99454951 @default.
• W3074772937 hasConceptScore W3074772937C126322002 @default.
• W3074772937 hasConceptScore W3074772937C141071460 @default.
• W3074772937 hasConceptScore W3074772937C151730666 @default.
• W3074772937 hasConceptScore W3074772937C159110408 @default.
• W3074772937 hasConceptScore W3074772937C167135981 @default.
• W3074772937 hasConceptScore W3074772937C2778589496 @default.
• W3074772937 hasConceptScore W3074772937C2779343474 @default.
• W3074772937 hasConceptScore W3074772937C2908647359 @default.
• W3074772937 hasConceptScore W3074772937C2994186709 @default.
• W3074772937 hasConceptScore W3074772937C509974204 @default.
• W3074772937 hasConceptScore W3074772937C71924100 @default.
• W3074772937 hasConceptScore W3074772937C86803240 @default.
• W3074772937 hasConceptScore W3074772937C99454951 @default.
• W3074772937 hasFunder F4320309499 @default.
• W3074772937 hasFunder F4320309603 @default.
• W3074772937 hasIssue "2" @default.
• W3074772937 hasLocation W30747729371 @default.
• W3074772937 hasOpenAccess W3074772937 @default.
• W3074772937 hasPrimaryLocation W30747729371 @default.
• W3074772937 hasRelatedWork W113810927 @default.
• W3074772937 hasRelatedWork W1586374228 @default.
• W3074772937 hasRelatedWork W2003938723 @default.
• W3074772937 hasRelatedWork W2047967234 @default.
• W3074772937 hasRelatedWork W2118496982 @default.
• W3074772937 hasRelatedWork W2364998975 @default.
• W3074772937 hasRelatedWork W2369162477 @default.
• W3074772937 hasRelatedWork W2439875401 @default.
• W3074772937 hasRelatedWork W4238867864 @default.
• W3074772937 hasRelatedWork W2525756941 @default.
• W3074772937 hasVolume "61" @default.
• W3074772937 isParatext "false" @default.
• W3074772937 isRetracted "false" @default.
• W3074772937 magId "3074772937" @default.

• next