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- W307817388 abstract "The ionic requirements for the action of a wide range of stimuli of insulin secretion have been studied. Extracellular sodium and calcium are essential and procedures designed to raise intracellular sodium concentration stimulate secretion. The existence in the β-cell of a sodium-dependent calcium uptake process is postulated. It is suggested that a late event in the stimulation of insulin secretion involves Ca++ uptake by the β-cell through this process. The inhibition of many stimuli of insulin secretion by anoxia or dinitrophenol suggests that a late stage in the release mechanism requires ATP." @default.
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- W307817388 date "1970-01-01" @default.
- W307817388 modified "2023-10-16" @default.
- W307817388 title "IONIC MECHANISMS IN THE REGULATION OF INSULIN SECRETION" @default.
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- W307817388 doi "https://doi.org/10.1016/b978-0-08-015844-0.50055-9" @default.
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