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- W3079889908 endingPage "173" @default.
- W3079889908 startingPage "166" @default.
- W3079889908 abstract "Melasma, a common cause for seeking dermatologic care, is a chronic condition of skin hyperpigmentation. With a poorly understood pathogenesis, and no universal cure, melasma is a challenge for many dermatologists. For decades, there has been investigation into the role of oxidative stress in melasma. In this literature review, we introduce the role of oxidative stress in melasma and discuss the function of various topical and oral antioxidant therapies for patients suffering from melasma. Numerous studies have shown efficacy of various antioxidant therapies for treatment of hyperpigmentation, and in this review, we focus primarily on those with less widespread use. Vitamin E, niacinamide, polypodium leucotomos, pycnogenol, grape seed extract, amino fruit acids, phytic acid, zinc, silymarin, Korean red ginseng powder, plant extracts, and parsley all have well-demonstrated evidence of antioxidant properties, and these substances have been studied in the context of skin hyperpigmentation. Although there is conflicting evidence of their therapeutic efficacy, the use of these naturally occurring substances is promising for patients and medical providers seeking alternative therapeutic options." @default.
- W3079889908 created "2020-08-24" @default.
- W3079889908 creator A5017611684 @default.
- W3079889908 creator A5025315123 @default.
- W3079889908 creator A5052346574 @default.
- W3079889908 date "2020-08-20" @default.
- W3079889908 modified "2023-10-01" @default.
- W3079889908 title "Treatment of melasma: a review of less commonly used antioxidants" @default.
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- W3079889908 doi "https://doi.org/10.1111/ijd.15133" @default.
- W3079889908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32815582" @default.
- W3079889908 hasPublicationYear "2020" @default.