FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080110602> ?p ?o ?g. }

• W3080110602 endingPage "147" @default.
• W3080110602 startingPage "138" @default.
• W3080110602 abstract "Demographic projections for hip fragility fractures indicate a rising annual incidence by virtue of a multimorbid, ageing population with more noncommunicable diseases (NCDs). NCDs are characterised by slow progression and long duration ranging from ischaemic cardiovascular disease, cerebrovascular disease, diabetes, chronic obstructive pulmonary disease to various cancers. Management of this disease burden often involves commencing patients on oral anticoagulants to reduce the risk of thromboembolic events. The use of direct oral anticoagulants (DOACs) in clinical practice has increased due to their rapid onset of action, short half-life and predictable anticoagulant effects, without the need for routine monitoring. Safe and timely surgical intervention relies on reversal of anticoagulants. However, the lack of specific evidence-based guidelines for the perioperative management of patients on DOACs with hip fractures has proved challenging; in particular, the accessibility of DOAC-specific assays, justification of the cost-benefit ratio of targeted reversal agents and indications for neuraxial anaesthesia. This has led to potentially avoidable delays in surgical intervention. Following a literature review of the pharmacokinetic and pharmacodynamics of commonly used DOACs in our region including the role of surrogate markers, we propose a systematic, evidence-based guideline to the perioperative management of hip fractures DOACs. We believe this standardised protocol can be easily replicated between hospitals. We recommend that if patients are deemed suitable for a general anaesthesia, with satisfactory renal function, optimal surgical time should be 24 h following the last ingested dose of DOAC." @default.
• W3080110602 created "2020-09-01" @default.
• W3080110602 creator A5010466546 @default.
• W3080110602 creator A5038496775 @default.
• W3080110602 creator A5039996190 @default.
• W3080110602 creator A5064535063 @default.
• W3080110602 creator A5071594230 @default.
• W3080110602 date "2021-01-01" @default.
• W3080110602 modified "2023-09-29" @default.
• W3080110602 title "Direct oral anticoagulants (DOACs) and neck of femur fractures: Standardising the perioperative management and time to surgery" @default.
• W3080110602 cites W1485772655 @default.
• W3080110602 cites W1507763452 @default.
• W3080110602 cites W1547997477 @default.
• W3080110602 cites W1568662837 @default.
• W3080110602 cites W1842328209 @default.
• W3080110602 cites W1895596777 @default.
• W3080110602 cites W1965372343 @default.
• W3080110602 cites W1965492206 @default.
• W3080110602 cites W1967129589 @default.
• W3080110602 cites W1974535354 @default.
• W3080110602 cites W1984449254 @default.
• W3080110602 cites W1989930316 @default.
• W3080110602 cites W1999948625 @default.
• W3080110602 cites W2001598988 @default.
• W3080110602 cites W2008955498 @default.
• W3080110602 cites W2017582897 @default.
• W3080110602 cites W2021621876 @default.
• W3080110602 cites W2027735039 @default.
• W3080110602 cites W2027863730 @default.
• W3080110602 cites W2032980606 @default.
• W3080110602 cites W2035077408 @default.
• W3080110602 cites W2045987573 @default.
• W3080110602 cites W2057065644 @default.
• W3080110602 cites W2057272755 @default.
• W3080110602 cites W2058927570 @default.
• W3080110602 cites W2060580339 @default.
• W3080110602 cites W2062696489 @default.
• W3080110602 cites W2083035480 @default.
• W3080110602 cites W2084904145 @default.
• W3080110602 cites W2096246254 @default.
• W3080110602 cites W2097854437 @default.
• W3080110602 cites W2108651983 @default.
• W3080110602 cites W2109450134 @default.
• W3080110602 cites W2113446992 @default.
• W3080110602 cites W2114189419 @default.
• W3080110602 cites W2115513773 @default.
• W3080110602 cites W2123446579 @default.
• W3080110602 cites W2124882231 @default.
• W3080110602 cites W2133686162 @default.
• W3080110602 cites W2148984742 @default.
• W3080110602 cites W2149388786 @default.
• W3080110602 cites W2151514200 @default.
• W3080110602 cites W2152623033 @default.
• W3080110602 cites W2152957042 @default.
• W3080110602 cites W2153438515 @default.
• W3080110602 cites W2156611099 @default.
• W3080110602 cites W2156970332 @default.
• W3080110602 cites W2160625453 @default.
• W3080110602 cites W2166402206 @default.
• W3080110602 cites W2169096805 @default.
• W3080110602 cites W2170251955 @default.
• W3080110602 cites W2174386486 @default.
• W3080110602 cites W2339769319 @default.
• W3080110602 cites W2514338974 @default.
• W3080110602 cites W2526553122 @default.
• W3080110602 cites W2551278876 @default.
• W3080110602 cites W2553572012 @default.
• W3080110602 cites W2557845780 @default.
• W3080110602 cites W2580216138 @default.
• W3080110602 cites W2617973506 @default.
• W3080110602 cites W2799614734 @default.
• W3080110602 cites W2802235434 @default.
• W3080110602 cites W2894712992 @default.
• W3080110602 cites W2895359358 @default.
• W3080110602 cites W2899159809 @default.
• W3080110602 cites W2914381505 @default.
• W3080110602 cites W2923449096 @default.
• W3080110602 cites W2973500087 @default.
• W3080110602 doi "https://doi.org/10.1016/j.jcot.2020.08.005" @default.
• W3080110602 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7920209" @default.
• W3080110602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33716439" @default.
• W3080110602 hasPublicationYear "2021" @default.
• W3080110602 type Work @default.
• W3080110602 sameAs 3080110602 @default.
• W3080110602 citedByCount "5" @default.
• W3080110602 countsByYear W30801106022022 @default.
• W3080110602 countsByYear W30801106022023 @default.
• W3080110602 crossrefType "journal-article" @default.
• W3080110602 hasAuthorship W3080110602A5010466546 @default.
• W3080110602 hasAuthorship W3080110602A5038496775 @default.
• W3080110602 hasAuthorship W3080110602A5039996190 @default.
• W3080110602 hasAuthorship W3080110602A5064535063 @default.
• W3080110602 hasAuthorship W3080110602A5071594230 @default.
• W3080110602 hasBestOaLocation W30801106021 @default.
• W3080110602 hasConcept C126322002 @default.
• W3080110602 hasConcept C141071460 @default.
• W3080110602 hasConcept C142724271 @default.
• W3080110602 hasConcept C177713679 @default.

• next