Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080202988> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W3080202988 endingPage "596" @default.
- W3080202988 startingPage "592" @default.
- W3080202988 abstract "Diabetes mellitus (DM) has harmful effects on body organs, including submandibular salivary glands (SMGs). It impairs wound healing process that follow sialoadenectomy. Yet there is no complete cure to diabetes, the available medications tend to control the side effects of DM or manage insulin resistance. Herein we tried to investigate the possible effects of injectable platelet rich fibrin (i-PRF) and melatonin on wound healing in diabetic rats.Surgical defects were created in SMGs of 30 rats after confirmation of DM induction. Then rats were randomly and equally allocated into three groups. Group I served as control group; group II received topically applied i-PRF, and group III received topically administrated melatonin. After 28 days all rats were euthanized, and SMGs were processed for histological and biochemical analysis.Both i-PRF and melatonin caused significant reduction of malondialdehyde (P < 0.0001) and caspase-3 (P < 0.001) and significant increase in vascular endothelial growth factors (P = 0.001,0.009 respectively) that increased SMGs regenerative capacity when compared to diabetic group. Melatonin showed superior results regarding the histomorphological structure of SMGs.Melatonin and i-PRF can be possible candidates for improvement of wound healing events in SMGs of diabetic rats." @default.
- W3080202988 created "2020-09-01" @default.
- W3080202988 creator A5021399637 @default.
- W3080202988 creator A5065504632 @default.
- W3080202988 date "2020-10-01" @default.
- W3080202988 modified "2023-09-26" @default.
- W3080202988 title "Effect of melatonin versus injectable platelet rich fibrin on critical wound healing in submandibular salivary glands of diabetic rats" @default.
- W3080202988 cites W1973703381 @default.
- W3080202988 cites W1973935082 @default.
- W3080202988 cites W1976464405 @default.
- W3080202988 cites W1987714633 @default.
- W3080202988 cites W2004091818 @default.
- W3080202988 cites W2008958430 @default.
- W3080202988 cites W2017394814 @default.
- W3080202988 cites W2025419894 @default.
- W3080202988 cites W2026996407 @default.
- W3080202988 cites W2042579895 @default.
- W3080202988 cites W2053054955 @default.
- W3080202988 cites W2071638959 @default.
- W3080202988 cites W2098615221 @default.
- W3080202988 cites W2105740912 @default.
- W3080202988 cites W2313834017 @default.
- W3080202988 cites W2397096096 @default.
- W3080202988 cites W2464983768 @default.
- W3080202988 cites W2575704018 @default.
- W3080202988 cites W2584707707 @default.
- W3080202988 cites W2595772711 @default.
- W3080202988 cites W2620363223 @default.
- W3080202988 cites W2724793051 @default.
- W3080202988 cites W2750856430 @default.
- W3080202988 cites W2848182954 @default.
- W3080202988 cites W2965105701 @default.
- W3080202988 doi "https://doi.org/10.1016/j.jobcr.2020.08.016" @default.
- W3080202988 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7484547" @default.
- W3080202988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32953441" @default.
- W3080202988 hasPublicationYear "2020" @default.
- W3080202988 type Work @default.
- W3080202988 sameAs 3080202988 @default.
- W3080202988 citedByCount "8" @default.
- W3080202988 countsByYear W30802029882021 @default.
- W3080202988 countsByYear W30802029882022 @default.
- W3080202988 countsByYear W30802029882023 @default.
- W3080202988 crossrefType "journal-article" @default.
- W3080202988 hasAuthorship W3080202988A5021399637 @default.
- W3080202988 hasAuthorship W3080202988A5065504632 @default.
- W3080202988 hasBestOaLocation W30802029882 @default.
- W3080202988 hasConcept C126322002 @default.
- W3080202988 hasConcept C134018914 @default.
- W3080202988 hasConcept C141071460 @default.
- W3080202988 hasConcept C203014093 @default.
- W3080202988 hasConcept C2777560349 @default.
- W3080202988 hasConcept C2778182776 @default.
- W3080202988 hasConcept C2780266248 @default.
- W3080202988 hasConcept C2780269544 @default.
- W3080202988 hasConcept C54173615 @default.
- W3080202988 hasConcept C555293320 @default.
- W3080202988 hasConcept C71924100 @default.
- W3080202988 hasConceptScore W3080202988C126322002 @default.
- W3080202988 hasConceptScore W3080202988C134018914 @default.
- W3080202988 hasConceptScore W3080202988C141071460 @default.
- W3080202988 hasConceptScore W3080202988C203014093 @default.
- W3080202988 hasConceptScore W3080202988C2777560349 @default.
- W3080202988 hasConceptScore W3080202988C2778182776 @default.
- W3080202988 hasConceptScore W3080202988C2780266248 @default.
- W3080202988 hasConceptScore W3080202988C2780269544 @default.
- W3080202988 hasConceptScore W3080202988C54173615 @default.
- W3080202988 hasConceptScore W3080202988C555293320 @default.
- W3080202988 hasConceptScore W3080202988C71924100 @default.
- W3080202988 hasIssue "4" @default.
- W3080202988 hasLocation W30802029881 @default.
- W3080202988 hasLocation W30802029882 @default.
- W3080202988 hasLocation W30802029883 @default.
- W3080202988 hasOpenAccess W3080202988 @default.
- W3080202988 hasPrimaryLocation W30802029881 @default.
- W3080202988 hasRelatedWork W1980207544 @default.
- W3080202988 hasRelatedWork W1993990081 @default.
- W3080202988 hasRelatedWork W2009692691 @default.
- W3080202988 hasRelatedWork W2017830665 @default.
- W3080202988 hasRelatedWork W2031318332 @default.
- W3080202988 hasRelatedWork W2038780749 @default.
- W3080202988 hasRelatedWork W2052448036 @default.
- W3080202988 hasRelatedWork W2058382634 @default.
- W3080202988 hasRelatedWork W2075463443 @default.
- W3080202988 hasRelatedWork W2133675714 @default.
- W3080202988 hasVolume "10" @default.
- W3080202988 isParatext "false" @default.
- W3080202988 isRetracted "false" @default.
- W3080202988 magId "3080202988" @default.
- W3080202988 workType "article" @default.