Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080263191> ?p ?o ?g. }
- W3080263191 endingPage "306" @default.
- W3080263191 startingPage "306" @default.
- W3080263191 abstract "Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18, 20 or 22 carbon atoms, which have been found able to counteract cardiovascular diseases. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in particular, have been found to produce both vaso- and cardio-protective response via modulation of membrane phospholipids thereby improving cardiac mitochondrial functions and energy production. However, antioxidant properties of n-3 PUFAs, along with their anti-inflammatory effect in both blood vessels and cardiac cells, seem to exert beneficial effects in cardiovascular impairment. In fact, dietary supplementation with n-3 PUFAs has been demonstrated to reduce oxidative stress-related mitochondrial dysfunction and endothelial cell apoptosis, an effect occurring via an increased activity of endogenous antioxidant enzymes. On the other hand, n-3 PUFAs have been shown to counteract the release of pro-inflammatory cytokines in both vascular tissues and in the myocardium, thereby restoring vascular reactivity and myocardial performance. Here we summarize the molecular mechanisms underlying the anti-oxidant and anti-inflammatory effect of n-3 PUFAs in vascular and cardiac tissues and their implication in the prevention and treatment of cardiovascular disease." @default.
- W3080263191 created "2020-09-01" @default.
- W3080263191 creator A5022525298 @default.
- W3080263191 creator A5026027505 @default.
- W3080263191 creator A5030357609 @default.
- W3080263191 creator A5039683060 @default.
- W3080263191 creator A5041583034 @default.
- W3080263191 creator A5045505516 @default.
- W3080263191 creator A5046208546 @default.
- W3080263191 creator A5049086897 @default.
- W3080263191 creator A5059314991 @default.
- W3080263191 creator A5069260907 @default.
- W3080263191 creator A5070957587 @default.
- W3080263191 creator A5072922882 @default.
- W3080263191 creator A5077577527 @default.
- W3080263191 creator A5081979403 @default.
- W3080263191 creator A5085426785 @default.
- W3080263191 creator A5088103468 @default.
- W3080263191 date "2020-08-25" @default.
- W3080263191 modified "2023-10-06" @default.
- W3080263191 title "The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection" @default.
- W3080263191 cites W1275357281 @default.
- W3080263191 cites W1668359592 @default.
- W3080263191 cites W1675525438 @default.
- W3080263191 cites W1685345777 @default.
- W3080263191 cites W1809795104 @default.
- W3080263191 cites W1937978193 @default.
- W3080263191 cites W1984887754 @default.
- W3080263191 cites W1986330546 @default.
- W3080263191 cites W2006967429 @default.
- W3080263191 cites W2009458118 @default.
- W3080263191 cites W2017758052 @default.
- W3080263191 cites W2017979664 @default.
- W3080263191 cites W2019441433 @default.
- W3080263191 cites W2019582654 @default.
- W3080263191 cites W2032824150 @default.
- W3080263191 cites W2033766456 @default.
- W3080263191 cites W2034696183 @default.
- W3080263191 cites W2039274814 @default.
- W3080263191 cites W2040165379 @default.
- W3080263191 cites W2040651415 @default.
- W3080263191 cites W2043336678 @default.
- W3080263191 cites W2044987818 @default.
- W3080263191 cites W2047080616 @default.
- W3080263191 cites W2054225508 @default.
- W3080263191 cites W2057838422 @default.
- W3080263191 cites W2059747893 @default.
- W3080263191 cites W2061978890 @default.
- W3080263191 cites W2064114884 @default.
- W3080263191 cites W2064755830 @default.
- W3080263191 cites W2065295548 @default.
- W3080263191 cites W2070313752 @default.
- W3080263191 cites W2072078713 @default.
- W3080263191 cites W2073674694 @default.
- W3080263191 cites W2074171583 @default.
- W3080263191 cites W2078889151 @default.
- W3080263191 cites W2081374800 @default.
- W3080263191 cites W2090609282 @default.
- W3080263191 cites W2093614380 @default.
- W3080263191 cites W2096505980 @default.
- W3080263191 cites W2100851898 @default.
- W3080263191 cites W2106624438 @default.
- W3080263191 cites W2109654316 @default.
- W3080263191 cites W2117371402 @default.
- W3080263191 cites W2119396757 @default.
- W3080263191 cites W2124494071 @default.
- W3080263191 cites W2125620896 @default.
- W3080263191 cites W2128788220 @default.
- W3080263191 cites W2135909428 @default.
- W3080263191 cites W2138695494 @default.
- W3080263191 cites W2139086060 @default.
- W3080263191 cites W2140032954 @default.
- W3080263191 cites W2149318526 @default.
- W3080263191 cites W2157005899 @default.
- W3080263191 cites W2161192211 @default.
- W3080263191 cites W2163652905 @default.
- W3080263191 cites W2167075471 @default.
- W3080263191 cites W2171749815 @default.
- W3080263191 cites W2171898474 @default.
- W3080263191 cites W2173188733 @default.
- W3080263191 cites W2178618967 @default.
- W3080263191 cites W2183621056 @default.
- W3080263191 cites W2185869224 @default.
- W3080263191 cites W2192064401 @default.
- W3080263191 cites W2217305406 @default.
- W3080263191 cites W2218259197 @default.
- W3080263191 cites W2227154220 @default.
- W3080263191 cites W2233154905 @default.
- W3080263191 cites W2264702236 @default.
- W3080263191 cites W2266347880 @default.
- W3080263191 cites W2291723671 @default.
- W3080263191 cites W2307088680 @default.
- W3080263191 cites W2347152603 @default.
- W3080263191 cites W2417784915 @default.
- W3080263191 cites W2470082080 @default.
- W3080263191 cites W2471215771 @default.
- W3080263191 cites W247394393 @default.
- W3080263191 cites W2483228038 @default.