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- W3080293067 endingPage "91" @default.
- W3080293067 startingPage "75" @default.
- W3080293067 abstract "Photocleavable biomaterials and bioconjugates are particularly interesting because light sources are easy to obtain and the responsiveness of materials is convenient to control. In recent years, various photocleavable biomaterials and bioconjugates have been synthesized for the control of payload release, regulation of biomolecule activity, 3D cell culture, and investigation of molecular mechanisms. Photocleavable linkers are crucial components of photocleavable biomaterials, which significantly influence the photoresponsive capabilities of materials. Photosensitive molecules, such as o-nitrobenzyls and coumarins, have been extensively developed as photocleavable linkers. In the present review, we provide comprehensive knowledge regarding the synthetic strategies of o-nitrobenzyl and coumarin derived linkers with various functional groups and their applications for the construction of photocleavable biomaterials and bioconjugates. Finally, the biomedical applications of o-nitrobenzyl and coumarin-based photocleavable biomaterials and bioconjugates will be summarized and discussed." @default.
- W3080293067 created "2020-09-01" @default.
- W3080293067 creator A5025226017 @default.
- W3080293067 creator A5060696709 @default.
- W3080293067 creator A5075800943 @default.
- W3080293067 creator A5084271825 @default.
- W3080293067 date "2020-10-01" @default.
- W3080293067 modified "2023-10-10" @default.
- W3080293067 title "Approaches for the synthesis of o-nitrobenzyl and coumarin linkers for use in photocleavable biomaterials and bioconjugates and their biomedical applications" @default.
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