FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080319441> ?p ?o ?g. }

• W3080319441 endingPage "70" @default.
• W3080319441 startingPage "59" @default.
• W3080319441 abstract "Human breast milk (HM) contains multiple bioactive substances determining its impact on children's health. Extracellular vesicles (EVs) are a heterogeneous group of secreted nanoparticles that are present in HM and may be partially responsible for its beneficial effects. The precise roles and content of EVs in HM remain largely unknown. To examine this, we performed a short narrative review on the literature focusing on HM EVs to contextualize the available data, followed by a scoping review of MEDLINE and Embase databases. We identified 424 nonduplicate citations with 19 original studies included. In this perspective, we summarize the evidence around HM EVs, highlight some theoretical considerations based on existing evidence, and provide an overview of some challenges associated with the complexity and heterogeneity of EV research. We consider how the existing data from HM studies conform to the minimal information for studies of EVs (MISEV) guidelines. Across the studies a variety of research methods were utilized involving both bench-based and translational methods, and a range of different EV contents were examined including RNA, proteins, and glycopeptides. We observed a variety of health outcomes in these studies, including allergy and atopy, necrotizing enterocolitis, and HIV. While some promising results have been demonstrated, the heterogeneity in outcomes of interest, methodological limitations, and relatively small number of studies in the field make comparison between studies or further translational work problematic. To date, no studies have examined normative values of HM EVs in a large, diverse population or with respect to potentially important influencing factors such as timing (hind- vs. foremilk), stage (colostrum vs. mature milk), and infant age (preterm vs. term), which makes extrapolation from bench or basic research impossible. Future research should focus on addressing the current inadequacies in the literature and utilize MISEV guidelines to inform study design." @default.
• W3080319441 created "2020-09-01" @default.
• W3080319441 creator A5022984000 @default.
• W3080319441 creator A5023267835 @default.
• W3080319441 creator A5025160415 @default.
• W3080319441 creator A5029716976 @default.
• W3080319441 creator A5040583970 @default.
• W3080319441 creator A5051834816 @default.
• W3080319441 creator A5059826307 @default.
• W3080319441 creator A5064192758 @default.
• W3080319441 creator A5077452104 @default.
• W3080319441 creator A5084758555 @default.
• W3080319441 date "2021-01-01" @default.
• W3080319441 modified "2023-10-16" @default.
• W3080319441 title "Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease" @default.
• W3080319441 cites W1538522759 @default.
• W3080319441 cites W1560283302 @default.
• W3080319441 cites W1859042441 @default.
• W3080319441 cites W1964370318 @default.
• W3080319441 cites W1986396552 @default.
• W3080319441 cites W1993713997 @default.
• W3080319441 cites W2005962589 @default.
• W3080319441 cites W2010049989 @default.
• W3080319441 cites W2016960054 @default.
• W3080319441 cites W2023906545 @default.
• W3080319441 cites W2036178413 @default.
• W3080319441 cites W2041174821 @default.
• W3080319441 cites W204171329 @default.
• W3080319441 cites W2069772889 @default.
• W3080319441 cites W2074584055 @default.
• W3080319441 cites W2097233439 @default.
• W3080319441 cites W2104116256 @default.
• W3080319441 cites W2115093090 @default.
• W3080319441 cites W2115093459 @default.
• W3080319441 cites W2117391818 @default.
• W3080319441 cites W2126465607 @default.
• W3080319441 cites W2129553691 @default.
• W3080319441 cites W2129802808 @default.
• W3080319441 cites W2129933222 @default.
• W3080319441 cites W2132003185 @default.
• W3080319441 cites W2136501202 @default.
• W3080319441 cites W2136601868 @default.
• W3080319441 cites W2155441983 @default.
• W3080319441 cites W2165817513 @default.
• W3080319441 cites W2168065604 @default.
• W3080319441 cites W2168448155 @default.
• W3080319441 cites W2223087481 @default.
• W3080319441 cites W2292254726 @default.
• W3080319441 cites W2313108251 @default.
• W3080319441 cites W2335418349 @default.
• W3080319441 cites W2499375112 @default.
• W3080319441 cites W2509259488 @default.
• W3080319441 cites W2528141940 @default.
• W3080319441 cites W2529648180 @default.
• W3080319441 cites W2549746211 @default.
• W3080319441 cites W2600399425 @default.
• W3080319441 cites W2605107433 @default.
• W3080319441 cites W2610575445 @default.
• W3080319441 cites W2612545873 @default.
• W3080319441 cites W2694847810 @default.
• W3080319441 cites W2727532420 @default.
• W3080319441 cites W2733152565 @default.
• W3080319441 cites W2740495409 @default.
• W3080319441 cites W2751524450 @default.
• W3080319441 cites W2752823190 @default.
• W3080319441 cites W2767951694 @default.
• W3080319441 cites W2790210772 @default.
• W3080319441 cites W2790363451 @default.
• W3080319441 cites W2798170384 @default.
• W3080319441 cites W2801899862 @default.
• W3080319441 cites W2801924187 @default.
• W3080319441 cites W2804596631 @default.
• W3080319441 cites W2807856097 @default.
• W3080319441 cites W2811208517 @default.
• W3080319441 cites W2834418161 @default.
• W3080319441 cites W2885557301 @default.
• W3080319441 cites W2889806779 @default.
• W3080319441 cites W2891378911 @default.
• W3080319441 cites W2895366538 @default.
• W3080319441 cites W2895445445 @default.
• W3080319441 cites W2897601525 @default.
• W3080319441 cites W2900756811 @default.
• W3080319441 cites W2936380002 @default.
• W3080319441 cites W2938080486 @default.
• W3080319441 cites W2944217984 @default.
• W3080319441 cites W2949335118 @default.
• W3080319441 cites W2951299640 @default.
• W3080319441 cites W2967888334 @default.
• W3080319441 doi "https://doi.org/10.1093/advances/nmaa094" @default.
• W3080319441 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7849950" @default.
• W3080319441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32838428" @default.
• W3080319441 hasPublicationYear "2021" @default.
• W3080319441 type Work @default.
• W3080319441 sameAs 3080319441 @default.
• W3080319441 citedByCount "18" @default.
• W3080319441 countsByYear W30803194412020 @default.
• W3080319441 countsByYear W30803194412021 @default.
• W3080319441 countsByYear W30803194412022 @default.

• next