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- W3080329705 abstract "Genetic analysis of canine parvovirus type 2 (CPV-2) variants circulating in South Eastern Nigeria was investigated. The original strain of CPV-2 emerged in 1978, mutated later to CPV-2a and has continued to be evolved.To genetically characterize CPV-2 strains detected in dogs in South Eastern Nigeria and to phylogenetically group the viruses with existing sequencing data.A total number of 82 rectal swabs were collected and stored in virus transport medium (VTM) from suspected cases of CPV-2 within the study area and were tested with polymerase chain reaction (PCR).Seventy-nine samples (96.3%) were positive for CPV-2 and sequence analysis of partial VP2 gene of 20 amplicons revealed circulation of CPV-2a (n=4) and CPV-2c (n=16) in the region. The obtained strains clustered together. However, the group was further divided into two clear clusters comprising of 2a and 2c strains. The vaccine strain and the CPV-2 reference strains from USA formed a monophyletic cluster.Canine parvovirus types 2a and 2c are co-circulating in South Eastern region of Nigeria and therefore, there is an urgent need for an improved vaccine to cover for the emerging strain (CPV-2c) in Nigeria." @default.
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- W3080329705 date "2020-01-01" @default.
- W3080329705 modified "2023-09-27" @default.
- W3080329705 title "Genetic analysis and emergence of canine parvovirus type 2c in South Eastern Nigeria." @default.
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