Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080401811> ?p ?o ?g. }
- W3080401811 abstract "Abstract Viral pathogens are being increasingly described in association with mass morbidity and mortality events in reptiles. However, our knowledge of reptile viruses and their role in population health remains limited. Herein, we describe a meta-transcriptomic investigation of a mass morbidity and mortality event in a colony of central bearded dragons ( Pogona vitticeps ) in 2014. Severe, extensive proliferation of the respiratory epithelium was consistently found in affected dragons. Similar proliferative lung lesions were identified in bearded dragons from the same colony in 2020 in association with increased intermittent mortality. Total RNA sequencing of bearded dragon tissue identified two divergent DNA viruses: a reptile-infecting circovirus, denoted bearded dragon circovirus (BDCV), and the first exogeneous reptilian chaphamaparvovirus - bearded dragon chaphamaparvovirus (BDchPV). Phylogenetic analysis revealed that BDCV was most closely related to bat-associated circoviruses, exhibiting 70% amino acid sequence identity. In contrast, the newly discovered BDchPV showed approximately 35-40% identity in the non-structural (NS) protein to parvoviruses obtained from tilapia fish and crocodiles in China. Subsequent specific PCR assays detected BDCV exclusively and comprehensively within animals with proliferative pulmonary lesions and respiratory disease. This study expands our understanding of viral diversity in the context of diseased reptiles in captivity." @default.
- W3080401811 created "2020-09-01" @default.
- W3080401811 creator A5001451166 @default.
- W3080401811 creator A5030773833 @default.
- W3080401811 creator A5033498337 @default.
- W3080401811 creator A5034398854 @default.
- W3080401811 creator A5050084023 @default.
- W3080401811 creator A5069660544 @default.
- W3080401811 creator A5081692774 @default.
- W3080401811 date "2020-08-24" @default.
- W3080401811 modified "2023-09-26" @default.
- W3080401811 title "Meta-transcriptomic discovery of a divergent circovirus and a chaphamaparvovirus in captive reptiles with proliferative respiratory syndrome" @default.
- W3080401811 cites W1502318192 @default.
- W3080401811 cites W1709649286 @default.
- W3080401811 cites W1965140957 @default.
- W3080401811 cites W1965562662 @default.
- W3080401811 cites W1974007058 @default.
- W3080401811 cites W1974293368 @default.
- W3080401811 cites W1978204300 @default.
- W3080401811 cites W1980547459 @default.
- W3080401811 cites W2011467709 @default.
- W3080401811 cites W2011657487 @default.
- W3080401811 cites W2030786687 @default.
- W3080401811 cites W2032391175 @default.
- W3080401811 cites W2045204781 @default.
- W3080401811 cites W2059088642 @default.
- W3080401811 cites W2102328093 @default.
- W3080401811 cites W2111647009 @default.
- W3080401811 cites W2124057117 @default.
- W3080401811 cites W2128880918 @default.
- W3080401811 cites W2131271579 @default.
- W3080401811 cites W2132789796 @default.
- W3080401811 cites W2133720120 @default.
- W3080401811 cites W2133796461 @default.
- W3080401811 cites W2145851495 @default.
- W3080401811 cites W2148748484 @default.
- W3080401811 cites W2153544371 @default.
- W3080401811 cites W2160378127 @default.
- W3080401811 cites W2165402511 @default.
- W3080401811 cites W2177763207 @default.
- W3080401811 cites W2236683171 @default.
- W3080401811 cites W2250033442 @default.
- W3080401811 cites W2304446115 @default.
- W3080401811 cites W2346016449 @default.
- W3080401811 cites W2466507028 @default.
- W3080401811 cites W2503002273 @default.
- W3080401811 cites W2508505967 @default.
- W3080401811 cites W2559838460 @default.
- W3080401811 cites W2626993137 @default.
- W3080401811 cites W2795052338 @default.
- W3080401811 cites W2810347659 @default.
- W3080401811 cites W2888292309 @default.
- W3080401811 cites W2916885210 @default.
- W3080401811 cites W2923960649 @default.
- W3080401811 cites W2940994144 @default.
- W3080401811 cites W2942004604 @default.
- W3080401811 cites W2947215407 @default.
- W3080401811 cites W2951981980 @default.
- W3080401811 cites W2953409974 @default.
- W3080401811 cites W2954152220 @default.
- W3080401811 cites W2967992487 @default.
- W3080401811 cites W2991011278 @default.
- W3080401811 cites W3002171535 @default.
- W3080401811 cites W3010486552 @default.
- W3080401811 cites W3023580286 @default.
- W3080401811 cites W3034944349 @default.
- W3080401811 cites W3038068978 @default.
- W3080401811 cites W4301484835 @default.
- W3080401811 doi "https://doi.org/10.1101/2020.08.24.264143" @default.
- W3080401811 hasPublicationYear "2020" @default.
- W3080401811 type Work @default.
- W3080401811 sameAs 3080401811 @default.
- W3080401811 citedByCount "3" @default.
- W3080401811 countsByYear W30804018112020 @default.
- W3080401811 countsByYear W30804018112021 @default.
- W3080401811 countsByYear W30804018112023 @default.
- W3080401811 crossrefType "posted-content" @default.
- W3080401811 hasAuthorship W3080401811A5001451166 @default.
- W3080401811 hasAuthorship W3080401811A5030773833 @default.
- W3080401811 hasAuthorship W3080401811A5033498337 @default.
- W3080401811 hasAuthorship W3080401811A5034398854 @default.
- W3080401811 hasAuthorship W3080401811A5050084023 @default.
- W3080401811 hasAuthorship W3080401811A5069660544 @default.
- W3080401811 hasAuthorship W3080401811A5081692774 @default.
- W3080401811 hasBestOaLocation W30804018111 @default.
- W3080401811 hasConcept C104317684 @default.
- W3080401811 hasConcept C126322002 @default.
- W3080401811 hasConcept C144024400 @default.
- W3080401811 hasConcept C149923435 @default.
- W3080401811 hasConcept C151730666 @default.
- W3080401811 hasConcept C159047783 @default.
- W3080401811 hasConcept C193252679 @default.
- W3080401811 hasConcept C2522874641 @default.
- W3080401811 hasConcept C2777914695 @default.
- W3080401811 hasConcept C2779231742 @default.
- W3080401811 hasConcept C2779343474 @default.
- W3080401811 hasConcept C2781045504 @default.
- W3080401811 hasConcept C2908647359 @default.
- W3080401811 hasConcept C54355233 @default.
- W3080401811 hasConcept C71924100 @default.