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- W3080423443 endingPage "283" @default.
- W3080423443 startingPage "259" @default.
- W3080423443 abstract "Abstract This book chapter provides a comprehensive overview of existing cell based therapies for repairing the injured heart. During a heart attack there is a permanent loss of cardiomyocytes, the muscle cells needed for the heart’s contractile activity. This irreversible loss of cardiomyocytes results in a decreased capacity of the heart to pump, an increased incidence of arrhythmia due to the formation of fibrous scar tissue, and in the long term, an increased risk of reoccurring heart attacks and ultimately heart failure. Presently, the only cure for heart failure is cardiac transplantation. For this reason, the idea of regenerating cardiomyocytes using cell based therapies has garnered the attention of both medical and scientific researchers. Cell based therapies offer the potential of less invasive forms of treatment and even the possibility of patient-specific medicine. Here we review several cell-therapy based approaches to cardiac regeneration including, the stimulation cardiomyocyte proliferation, the differentiation potential of progenitor cells, and the combined use of cell based therapies with bioengineering. A special focus will be given to the de novo generation of cardiomyocytes from somatic cells for patient-specific treatment. Lastly, these studies will be assessed for their present limitations and future potential as cardiac regeneration therapies." @default.
- W3080423443 created "2020-09-01" @default.
- W3080423443 creator A5014085457 @default.
- W3080423443 creator A5014942240 @default.
- W3080423443 creator A5028481056 @default.
- W3080423443 date "2020-01-01" @default.
- W3080423443 modified "2023-09-27" @default.
- W3080423443 title "Heart regeneration using somatic cells" @default.
- W3080423443 cites W1170563457 @default.
- W3080423443 cites W1548000125 @default.
- W3080423443 cites W1571391428 @default.
- W3080423443 cites W1576713661 @default.
- W3080423443 cites W1598852815 @default.
- W3080423443 cites W1603508604 @default.
- W3080423443 cites W1633362896 @default.
- W3080423443 cites W1806625111 @default.
- W3080423443 cites W1831212791 @default.
- W3080423443 cites W1889746212 @default.
- W3080423443 cites W1921778092 @default.
- W3080423443 cites W1966202908 @default.
- W3080423443 cites W1969038150 @default.
- W3080423443 cites W1970288681 @default.
- W3080423443 cites W1973433376 @default.
- W3080423443 cites W1975396117 @default.
- W3080423443 cites W1975617725 @default.
- W3080423443 cites W1976304560 @default.
- W3080423443 cites W1976935160 @default.
- W3080423443 cites W1977025496 @default.
- W3080423443 cites W1977437881 @default.
- W3080423443 cites W1978637982 @default.
- W3080423443 cites W1979868276 @default.
- W3080423443 cites W1982652699 @default.
- W3080423443 cites W1984778391 @default.
- W3080423443 cites W1986127144 @default.
- W3080423443 cites W1988229912 @default.
- W3080423443 cites W1989277100 @default.
- W3080423443 cites W1989583896 @default.
- W3080423443 cites W1991533533 @default.
- W3080423443 cites W1994957935 @default.
- W3080423443 cites W1995864831 @default.
- W3080423443 cites W1996668869 @default.
- W3080423443 cites W1996994627 @default.
- W3080423443 cites W1998147947 @default.
- W3080423443 cites W1998457769 @default.
- W3080423443 cites W1999126740 @default.
- W3080423443 cites W2000643914 @default.
- W3080423443 cites W2001356598 @default.
- W3080423443 cites W2003756136 @default.
- W3080423443 cites W2005400104 @default.
- W3080423443 cites W2006217199 @default.
- W3080423443 cites W2007394412 @default.
- W3080423443 cites W2008340135 @default.
- W3080423443 cites W2010031978 @default.
- W3080423443 cites W2010264692 @default.
- W3080423443 cites W2010417854 @default.
- W3080423443 cites W2016551277 @default.
- W3080423443 cites W2016854872 @default.
- W3080423443 cites W2018989038 @default.
- W3080423443 cites W2019720121 @default.
- W3080423443 cites W2019830818 @default.
- W3080423443 cites W2025899080 @default.
- W3080423443 cites W2026935410 @default.
- W3080423443 cites W2027225113 @default.
- W3080423443 cites W2028460986 @default.
- W3080423443 cites W2029971013 @default.
- W3080423443 cites W2032570745 @default.
- W3080423443 cites W2032617936 @default.
- W3080423443 cites W2033765226 @default.
- W3080423443 cites W2035631829 @default.
- W3080423443 cites W2038815755 @default.
- W3080423443 cites W2039501347 @default.
- W3080423443 cites W2040490208 @default.
- W3080423443 cites W2043246402 @default.
- W3080423443 cites W2046488302 @default.
- W3080423443 cites W204668112 @default.
- W3080423443 cites W2047286882 @default.
- W3080423443 cites W2047608515 @default.
- W3080423443 cites W2047760317 @default.
- W3080423443 cites W2051734098 @default.
- W3080423443 cites W2053348556 @default.
- W3080423443 cites W2053911973 @default.
- W3080423443 cites W2056140575 @default.
- W3080423443 cites W2058553784 @default.
- W3080423443 cites W2058950912 @default.
- W3080423443 cites W2060009170 @default.
- W3080423443 cites W2060791067 @default.
- W3080423443 cites W2060869747 @default.
- W3080423443 cites W2063550550 @default.
- W3080423443 cites W2064572992 @default.
- W3080423443 cites W2064752763 @default.
- W3080423443 cites W2066048575 @default.
- W3080423443 cites W2066390373 @default.
- W3080423443 cites W2068380542 @default.
- W3080423443 cites W2070515279 @default.
- W3080423443 cites W2070772918 @default.
- W3080423443 cites W2071765960 @default.
- W3080423443 cites W2072859865 @default.
- W3080423443 cites W2073420780 @default.