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• W3080452592 abstract "Progressive Supranuclear Palsy (PSP) is a rare, progressive, neurodegenerative disease characterized by postural instability and falls as well as vertical supranuclear gaze palsy (VSGP) defined as a clear limitation of the range of voluntary gaze in the vertical more than in the horizontal plane [ [1] Hoglinger G.U. Respondek G. Stamelou M. Kurz C. Josephs K.A. Lang A.E. Mollenhauer B. Muller U. Nilsson C. Whitwell J.L. Arzberger T. Englund E. Gelpi E. Giese A. Irwin D.J. Meissner W.G. Pantelyat A. Rajput A. van Swieten J.C. Troakes C. Antonini A. Bhatia K.P. Bordelon Y. Compta Y. Corvol J.C. Colosimo C. Dickson D.W. Dodel R. Ferguson L. Grossman M. Kassubek J. Krismer F. Levin J. Lorenzl S. Morris H.R. Nestor P. Oertel W.H. Poewe W. Rabinovici G. Rowe J.B. Schellenberg G.D. Seppi K. van Eimeren T. Wenning G.K. Boxer A.L. Golbe L.I. Litvan I. for the Movement Disorder Society-endorsed PSP Study Group Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Mov. Disord. 2017; 32: 853-864https://doi.org/10.1002/mds.26987 Crossref PubMed Scopus (980) Google Scholar ]. However, overt VSGP may be anticipated by either slowing of vertical saccades or the “round-the-houses” phenomenon (i.e., a curved trajectory of ocular movements when patients attempt to perform vertical saccades [ [2] Quinn N. The “round the houses” sign in progressive supranuclear palsy. Ann. Neurol. 1996; 40: 951https://doi.org/10.1002/ana.410400630 Crossref PubMed Scopus (39) Google Scholar ]). Herein, we describe two cases with a diagnosis of probable Richardson's syndrome (PSP-RS) according to the Movement Disorder Society (MDS) criteria [ [1] Hoglinger G.U. Respondek G. Stamelou M. Kurz C. Josephs K.A. Lang A.E. Mollenhauer B. Muller U. Nilsson C. Whitwell J.L. Arzberger T. Englund E. Gelpi E. Giese A. Irwin D.J. Meissner W.G. Pantelyat A. Rajput A. van Swieten J.C. Troakes C. Antonini A. Bhatia K.P. Bordelon Y. Compta Y. Corvol J.C. Colosimo C. Dickson D.W. Dodel R. Ferguson L. Grossman M. Kassubek J. Krismer F. Levin J. Lorenzl S. Morris H.R. Nestor P. Oertel W.H. Poewe W. Rabinovici G. Rowe J.B. Schellenberg G.D. Seppi K. van Eimeren T. Wenning G.K. Boxer A.L. Golbe L.I. Litvan I. for the Movement Disorder Society-endorsed PSP Study Group Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Mov. Disord. 2017; 32: 853-864https://doi.org/10.1002/mds.26987 Crossref PubMed Scopus (980) Google Scholar ], in whom a peculiar “zig-zag” conjugate movement, which was more prominent in the midline than in the extreme gaze positions, accompanied slowing of vertical saccades. This sign anticipated the development of VSGP." @default.
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• W3080452592 title "The “zig-zag” sign in Progressive Supranuclear Palsy" @default.
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• W3080452592 doi "https://doi.org/10.1016/j.parkreldis.2020.08.014" @default.
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