Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080453658> ?p ?o ?g. }
- W3080453658 endingPage "103" @default.
- W3080453658 startingPage "97" @default.
- W3080453658 abstract "Casein hydrolysate has been shown to improve arterial stiffness as estimated by brachial-ankle pulse wave velocity (baPWV) in untreated hypertensive patients. Facial pigmentation is associated with atherosclerosis, both of which are supposed to be modulated by tissue accumulation of advanced glycation end products (AGEs). However, effects of casein hydrolysate on facial pigmentation and AGEs remain largely unknown. This randomized double-blind placebo-controlled trial evaluated whether and how casein hydrolysate improves facial pigmentation in 80 nonhypertensive Japanese patients. Study participants were randomly assigned to receive either active tablets containing casein hydrolysate or placebo for 48 weeks. Facial pigmentation area, baPWV, and skin accumulation levels of AGEs were evaluated by Robo Skin Analyzer RSA50S II, volume–plethysmographic apparatus, and AGE Reader, respectively, at baseline and at the end of the intervention. Treatment with casein hydrolysate, but not placebo significantly reduced triglycerides and facial pigmentation area. There were significant differences of changes in triglycerides, facial pigmentation area, skin accumulation levels of AGEs, and baPWV between the two groups. Furthermore, changes in triglycerides and skin accumulation levels of AGEs were positively and independently associated with those in facial pigmentation area, whereas changes in baPWV were not. This study suggests that casein hydrolysate reduces facial pigmentation area in nonhypertensive participants partly by decreasing skin accumulation levels of AGEs. Clinical-Trials.gov ID: UMIN000027675." @default.
- W3080453658 created "2020-09-01" @default.
- W3080453658 creator A5002258037 @default.
- W3080453658 creator A5002564649 @default.
- W3080453658 creator A5016275110 @default.
- W3080453658 creator A5024470863 @default.
- W3080453658 creator A5030113532 @default.
- W3080453658 creator A5043805176 @default.
- W3080453658 creator A5084302861 @default.
- W3080453658 creator A5085153655 @default.
- W3080453658 date "2021-04-01" @default.
- W3080453658 modified "2023-09-23" @default.
- W3080453658 title "Casein Hydrolysate Containing Milk-Derived Peptides Reduces Facial Pigmentation Partly by Decreasing Advanced Glycation End Products in the Skin: A Randomized Double-Blind Placebo-Controlled Trial" @default.
- W3080453658 cites W1749025679 @default.
- W3080453658 cites W1996860127 @default.
- W3080453658 cites W2006724072 @default.
- W3080453658 cites W2014967635 @default.
- W3080453658 cites W2024426896 @default.
- W3080453658 cites W2040991102 @default.
- W3080453658 cites W2043424955 @default.
- W3080453658 cites W2057961754 @default.
- W3080453658 cites W2061999559 @default.
- W3080453658 cites W2068900191 @default.
- W3080453658 cites W2071259499 @default.
- W3080453658 cites W2092868109 @default.
- W3080453658 cites W2124454279 @default.
- W3080453658 cites W2125657956 @default.
- W3080453658 cites W2135195411 @default.
- W3080453658 cites W2138471025 @default.
- W3080453658 cites W2146106343 @default.
- W3080453658 cites W2150875608 @default.
- W3080453658 cites W2436595334 @default.
- W3080453658 cites W2510751088 @default.
- W3080453658 doi "https://doi.org/10.1089/rej.2020.2343" @default.
- W3080453658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32829654" @default.
- W3080453658 hasPublicationYear "2021" @default.
- W3080453658 type Work @default.
- W3080453658 sameAs 3080453658 @default.
- W3080453658 citedByCount "3" @default.
- W3080453658 countsByYear W30804536582022 @default.
- W3080453658 countsByYear W30804536582023 @default.
- W3080453658 crossrefType "journal-article" @default.
- W3080453658 hasAuthorship W3080453658A5002258037 @default.
- W3080453658 hasAuthorship W3080453658A5002564649 @default.
- W3080453658 hasAuthorship W3080453658A5016275110 @default.
- W3080453658 hasAuthorship W3080453658A5024470863 @default.
- W3080453658 hasAuthorship W3080453658A5030113532 @default.
- W3080453658 hasAuthorship W3080453658A5043805176 @default.
- W3080453658 hasAuthorship W3080453658A5084302861 @default.
- W3080453658 hasAuthorship W3080453658A5085153655 @default.
- W3080453658 hasConcept C126322002 @default.
- W3080453658 hasConcept C134018914 @default.
- W3080453658 hasConcept C142724271 @default.
- W3080453658 hasConcept C147990577 @default.
- W3080453658 hasConcept C185592680 @default.
- W3080453658 hasConcept C204787440 @default.
- W3080453658 hasConcept C27081682 @default.
- W3080453658 hasConcept C2775850156 @default.
- W3080453658 hasConcept C2776142715 @default.
- W3080453658 hasConcept C28800991 @default.
- W3080453658 hasConcept C31903555 @default.
- W3080453658 hasConcept C55493867 @default.
- W3080453658 hasConcept C555293320 @default.
- W3080453658 hasConcept C71924100 @default.
- W3080453658 hasConcept C84393581 @default.
- W3080453658 hasConcept C94412978 @default.
- W3080453658 hasConceptScore W3080453658C126322002 @default.
- W3080453658 hasConceptScore W3080453658C134018914 @default.
- W3080453658 hasConceptScore W3080453658C142724271 @default.
- W3080453658 hasConceptScore W3080453658C147990577 @default.
- W3080453658 hasConceptScore W3080453658C185592680 @default.
- W3080453658 hasConceptScore W3080453658C204787440 @default.
- W3080453658 hasConceptScore W3080453658C27081682 @default.
- W3080453658 hasConceptScore W3080453658C2775850156 @default.
- W3080453658 hasConceptScore W3080453658C2776142715 @default.
- W3080453658 hasConceptScore W3080453658C28800991 @default.
- W3080453658 hasConceptScore W3080453658C31903555 @default.
- W3080453658 hasConceptScore W3080453658C55493867 @default.
- W3080453658 hasConceptScore W3080453658C555293320 @default.
- W3080453658 hasConceptScore W3080453658C71924100 @default.
- W3080453658 hasConceptScore W3080453658C84393581 @default.
- W3080453658 hasConceptScore W3080453658C94412978 @default.
- W3080453658 hasIssue "2" @default.
- W3080453658 hasLocation W30804536581 @default.
- W3080453658 hasOpenAccess W3080453658 @default.
- W3080453658 hasPrimaryLocation W30804536581 @default.
- W3080453658 hasRelatedWork W1964573677 @default.
- W3080453658 hasRelatedWork W2021094548 @default.
- W3080453658 hasRelatedWork W2027399148 @default.
- W3080453658 hasRelatedWork W2087665565 @default.
- W3080453658 hasRelatedWork W2133385517 @default.
- W3080453658 hasRelatedWork W2185972736 @default.
- W3080453658 hasRelatedWork W2891026027 @default.
- W3080453658 hasRelatedWork W3018019434 @default.
- W3080453658 hasRelatedWork W3080453658 @default.
- W3080453658 hasRelatedWork W3111406397 @default.
- W3080453658 hasVolume "24" @default.
- W3080453658 isParatext "false" @default.