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- W3080494172 abstract "Introduction: A hoarse voice is often a benign symptom. Very rarely, it may be an ominous sign for a serious underlying disease. Due to the anatomical course of the recurrent laryngeal nerve, when compressed, it can lead to paralysis of the vocal cord. Several intrathoracic causes have been described in the literature, including mediastinal lymphadenopathy, malignancy such as lung cancer, cardiac tumors, and mitral stenosis. Aortic aneurysm and dissection are extremely rare causes of recurrent laryngeal nerve palsy but can cause significant morbidity and mortality if not diagnosed in a timely fashion. Case description: A 59-year-old male with longstanding hypertension, tobacco dependence presented with undiagnosed hoarseness for 8 months. On examination he was noted to have hypertensive urgency with blood pressure on 194/130 mmHg. Physical examination was otherwise unremarkable except for a prominent 4th heart sound on cardiac auscultation. He had mild anemia with a hemoglobin of 12.2 gm/dl. ECG was normal. Chest x-ray demonstrated a markedly enlarged aortic arch. Contrast CT scan of the chest demonstrated a dissecting aortic aneurysm measuring 6.4 cm in diameter, starting distal to the left subclavian artery with extension through the descending thoracic aorta, abdominal aorta, and terminating in the left iliac artery. Labetalol infusion was begun immediately. Flexible laryngoscopy showed that the left vocal cord was paralyzed in the paramedian position. Patient underwent thoracoabdominal aneurysm repair and re-implantation of left subclavian artery with a #18 mm tube graft. His hospital course was complicated with respiratory failure which required tracheostomy. Discussion: Ortner’s syndrome, first described in 1897, described left recurrent laryngeal nerve palsy caused by left atrial enlargement secondary to mitral stenosis. It is now also recognized as cardiovocal syndrome in which, albeit rarely, aortic aneurysms or dissection result in vocal cord immobility. Abrupt onset of chest pain is a common presentation of aortic dissection, yet 10% of patients present without pain. This case serves to demonstrate this phenomenon of hoarseness without accompanying pain as a highly atypical presentation of this disease. Early recognition can result in appropriate intervention prior to catastrophic event. Atypical presentations of common diseases often are a conundrum, and as a result, clinicians should raise their level of suspicion when history and physical exam are consistent with a possible problem even though the findings are not classic." @default.
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- W3080494172 date "2020-01-01" @default.
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- W3080494172 title "Painless dissecting aortic aneurysm presenting as a hoarse voice" @default.
- W3080494172 doi "https://doi.org/10.1016/j.aucc.2020.04.052" @default.
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