Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080619220> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3080619220 endingPage "626" @default.
- W3080619220 startingPage "620" @default.
- W3080619220 abstract "Haloarchaea are known to produce antimicrobial proteins, halocins which are generally stable at extreme conditions suggesting their potential biotechnological applications. Here, we report a halocin-producing haloarchaeon isolated from salt lake and identified as Haloferax larsenii HA4 using partial 16S rDNA sequence and biochemical properties. Whole-cell methanolysate showed ether-linked lipids, which is a characteristic feature of haloarchaea. Strain HA4 was able to grow at pH 6·0-10·0 and 15-30% NaCl. The growth response was normal but antimicrobial activity was detected only during the log-phase. Crude halocin HA4 was active in the pH range of pH 2·0-10·0 with stability up to 100°C. Cell-free supernatant (CFS) was also stable in different organic solvents and detergents tested. However, halocin activity was reduced after treatment with proteinase K suggesting the proteinaceous nature of the active compound. Concentrated CFS showed the presence of several proteins from 6·5-66 kDa but bioassay suggested ~14 kDa protein as halocin. Crude halocin preparation showed cytocidal activity against indicator strain, H. larsenii HA10 and inhibited the growth of other related strains such as H. larsenii HA3, HA8, HA9 and HA10." @default.
- W3080619220 created "2020-09-01" @default.
- W3080619220 creator A5055582042 @default.
- W3080619220 creator A5064311275 @default.
- W3080619220 date "2020-09-11" @default.
- W3080619220 modified "2023-09-24" @default.
- W3080619220 title "Identification and characterization of a halocin‐producing haloarchaeon isolated from Pachpadra salt lake" @default.
- W3080619220 cites W1484322702 @default.
- W3080619220 cites W1568127517 @default.
- W3080619220 cites W1927238348 @default.
- W3080619220 cites W2034688169 @default.
- W3080619220 cites W2049931481 @default.
- W3080619220 cites W2089673861 @default.
- W3080619220 cites W2091327817 @default.
- W3080619220 cites W2097934563 @default.
- W3080619220 cites W2113717587 @default.
- W3080619220 cites W2340719511 @default.
- W3080619220 cites W2461244872 @default.
- W3080619220 cites W2531788819 @default.
- W3080619220 cites W2620153415 @default.
- W3080619220 cites W2754857012 @default.
- W3080619220 cites W2761759734 @default.
- W3080619220 cites W2778884196 @default.
- W3080619220 cites W2792525224 @default.
- W3080619220 cites W4213248286 @default.
- W3080619220 doi "https://doi.org/10.1111/lam.13377" @default.
- W3080619220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32844475" @default.
- W3080619220 hasPublicationYear "2020" @default.
- W3080619220 type Work @default.
- W3080619220 sameAs 3080619220 @default.
- W3080619220 citedByCount "2" @default.
- W3080619220 countsByYear W30806192202021 @default.
- W3080619220 countsByYear W30806192202022 @default.
- W3080619220 crossrefType "journal-article" @default.
- W3080619220 hasAuthorship W3080619220A5055582042 @default.
- W3080619220 hasAuthorship W3080619220A5064311275 @default.
- W3080619220 hasConcept C109007969 @default.
- W3080619220 hasConcept C116834253 @default.
- W3080619220 hasConcept C151730666 @default.
- W3080619220 hasConcept C18903297 @default.
- W3080619220 hasConcept C2991991741 @default.
- W3080619220 hasConcept C86803240 @default.
- W3080619220 hasConcept C89423630 @default.
- W3080619220 hasConceptScore W3080619220C109007969 @default.
- W3080619220 hasConceptScore W3080619220C116834253 @default.
- W3080619220 hasConceptScore W3080619220C151730666 @default.
- W3080619220 hasConceptScore W3080619220C18903297 @default.
- W3080619220 hasConceptScore W3080619220C2991991741 @default.
- W3080619220 hasConceptScore W3080619220C86803240 @default.
- W3080619220 hasConceptScore W3080619220C89423630 @default.
- W3080619220 hasFunder F4320323670 @default.
- W3080619220 hasIssue "6" @default.
- W3080619220 hasLocation W30806192201 @default.
- W3080619220 hasOpenAccess W3080619220 @default.
- W3080619220 hasPrimaryLocation W30806192201 @default.
- W3080619220 hasRelatedWork W1977771343 @default.
- W3080619220 hasRelatedWork W1990804418 @default.
- W3080619220 hasRelatedWork W1993764875 @default.
- W3080619220 hasRelatedWork W2022067469 @default.
- W3080619220 hasRelatedWork W2046158694 @default.
- W3080619220 hasRelatedWork W2082860237 @default.
- W3080619220 hasRelatedWork W2130076355 @default.
- W3080619220 hasRelatedWork W2616533555 @default.
- W3080619220 hasRelatedWork W4317655616 @default.
- W3080619220 hasRelatedWork W1578520212 @default.
- W3080619220 hasVolume "71" @default.
- W3080619220 isParatext "false" @default.
- W3080619220 isRetracted "false" @default.
- W3080619220 magId "3080619220" @default.
- W3080619220 workType "article" @default.