FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080840344> ?p ?o ?g. }

• W3080840344 endingPage "787" @default.
• W3080840344 startingPage "787" @default.
• W3080840344 abstract "<br>Heat-shock proteins (HSPs) are a group of proteins that function to protect cells and tissues against different types of damage. The aim of this work was to study the relationship between the genetic variation in HSP70 genes and the risk for development of nephropathy in Egyptian patients with Type 2 diabetes mellitus (DM). This study was carried out on 90 patients divided into three groups: 30 patients of Type 2 DM with nephropathy (Group I), 30 patients of Type 2 DM without nephropathy (Group II) with duration of diabetes > 10 years in both patient groups, and 30 healthy persons, who served as controls (Group III). All the studied patients were submitted to full history taking, complete clinical examination, and laboratory investigations including fasting blood glucose, glycated hemoglobin, renal function tests, and urinary albumin- to-creatinine ratio. HSP70-1 -110 AC, +190 G/C, HSP70-2 +1267 A/G, and shock protein70- hom +2437 T/C gene polymorphism were determined using the polymerase chain reaction- restriction fragment length polymorphism technique (PCR-RFLP). The results of the present study showed a highly statistically significant difference between Group I and Group II regarding family history, systolic and diastolic blood pressure, and duration of diabetes. There was a significant difference in the distribution of C allele of HSP70-1 -110A/C and +190 G/C and G allele of <i>HSP70-2+1267A/G</i> with more frequent detection in nephropathy group versus other groups, while there was no significant difference in genotype and allele distributions among the three studied groups for the <i>HSP70-hom</i>. It can be concluded that the C allele distribution of (HSP70-1 -110 A/C and HSP70+190 C/G) and the G allele distribution of HSP70-2 +1267A/G are associated with the susceptibility to renal complications in Egyptian patients with Type 2 DM.<br>" @default.
• W3080840344 created "2020-09-01" @default.
• W3080840344 creator A5013614863 @default.
• W3080840344 creator A5040939130 @default.
• W3080840344 date "2020-01-01" @default.
• W3080840344 modified "2023-10-17" @default.
• W3080840344 title "Heat Shock Protein 70 Gene Polymorphism in Egyptian Patients with Type 2 Diabetes Mellitus, with and without Nephropathy" @default.
• W3080840344 cites W1589572279 @default.
• W3080840344 cites W1873110099 @default.
• W3080840344 cites W1985446951 @default.
• W3080840344 cites W2014862688 @default.
• W3080840344 cites W2030592587 @default.
• W3080840344 cites W2031566338 @default.
• W3080840344 cites W2041086782 @default.
• W3080840344 cites W2056959245 @default.
• W3080840344 cites W2083501599 @default.
• W3080840344 cites W2104736981 @default.
• W3080840344 cites W2143642040 @default.
• W3080840344 cites W2158596993 @default.
• W3080840344 cites W2160902434 @default.
• W3080840344 cites W2169018817 @default.
• W3080840344 doi "https://doi.org/10.4103/1319-2442.292312" @default.
• W3080840344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32801239" @default.
• W3080840344 hasPublicationYear "2020" @default.
• W3080840344 type Work @default.
• W3080840344 sameAs 3080840344 @default.
• W3080840344 citedByCount "3" @default.
• W3080840344 countsByYear W30808403442022 @default.
• W3080840344 countsByYear W30808403442023 @default.
• W3080840344 crossrefType "journal-article" @default.
• W3080840344 hasAuthorship W3080840344A5013614863 @default.
• W3080840344 hasAuthorship W3080840344A5040939130 @default.
• W3080840344 hasBestOaLocation W30808403441 @default.
• W3080840344 hasConcept C104317684 @default.
• W3080840344 hasConcept C126322002 @default.
• W3080840344 hasConcept C134018914 @default.
• W3080840344 hasConcept C135763542 @default.
• W3080840344 hasConcept C159641895 @default.
• W3080840344 hasConcept C168007829 @default.
• W3080840344 hasConcept C180754005 @default.
• W3080840344 hasConcept C2777180221 @default.
• W3080840344 hasConcept C2777538456 @default.
• W3080840344 hasConcept C2779922275 @default.
• W3080840344 hasConcept C2780306776 @default.
• W3080840344 hasConcept C2781184683 @default.
• W3080840344 hasConcept C2910068830 @default.
• W3080840344 hasConcept C54355233 @default.
• W3080840344 hasConcept C555293320 @default.
• W3080840344 hasConcept C71924100 @default.
• W3080840344 hasConcept C86803240 @default.
• W3080840344 hasConcept C90924648 @default.
• W3080840344 hasConceptScore W3080840344C104317684 @default.
• W3080840344 hasConceptScore W3080840344C126322002 @default.
• W3080840344 hasConceptScore W3080840344C134018914 @default.
• W3080840344 hasConceptScore W3080840344C135763542 @default.
• W3080840344 hasConceptScore W3080840344C159641895 @default.
• W3080840344 hasConceptScore W3080840344C168007829 @default.
• W3080840344 hasConceptScore W3080840344C180754005 @default.
• W3080840344 hasConceptScore W3080840344C2777180221 @default.
• W3080840344 hasConceptScore W3080840344C2777538456 @default.
• W3080840344 hasConceptScore W3080840344C2779922275 @default.
• W3080840344 hasConceptScore W3080840344C2780306776 @default.
• W3080840344 hasConceptScore W3080840344C2781184683 @default.
• W3080840344 hasConceptScore W3080840344C2910068830 @default.
• W3080840344 hasConceptScore W3080840344C54355233 @default.
• W3080840344 hasConceptScore W3080840344C555293320 @default.
• W3080840344 hasConceptScore W3080840344C71924100 @default.
• W3080840344 hasConceptScore W3080840344C86803240 @default.
• W3080840344 hasConceptScore W3080840344C90924648 @default.
• W3080840344 hasIssue "4" @default.
• W3080840344 hasLocation W30808403441 @default.
• W3080840344 hasOpenAccess W3080840344 @default.
• W3080840344 hasPrimaryLocation W30808403441 @default.
• W3080840344 hasRelatedWork W1971350538 @default.
• W3080840344 hasRelatedWork W1974938188 @default.
• W3080840344 hasRelatedWork W1977092444 @default.
• W3080840344 hasRelatedWork W1992169571 @default.
• W3080840344 hasRelatedWork W2063663752 @default.
• W3080840344 hasRelatedWork W2352995170 @default.
• W3080840344 hasRelatedWork W2375214247 @default.
• W3080840344 hasRelatedWork W2564413924 @default.
• W3080840344 hasRelatedWork W3175204269 @default.
• W3080840344 hasRelatedWork W142180345 @default.
• W3080840344 hasVolume "31" @default.
• W3080840344 isParatext "false" @default.
• W3080840344 isRetracted "false" @default.
• W3080840344 magId "3080840344" @default.
• W3080840344 workType "article" @default.