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- W3080931063 abstract "We have developed a low-cost, portable lab-on-a-valve (LOV) integrated microdevice for the detection of pathogens in primary-diagnosis settings. This system was designed for field-based pathogen detection based on the aggregation of gold nanoparticles induced by a switchable linker. A three-way valve, which has attracted much attention as a functional mesofluidic platform for pressure-driven flow, has been designed as a universal reaction platform that combines the functions of fluid flow and a reaction chamber. In addition, we obtain rapid and enhanced visual signals by the use of a syringe filter to remove gold nano-aggregates (Au NAs). Using this device, Salmonella Typhimurium down to 101 CFU mL-1 can be visually detected within 30 min by performing a simple operation that requires no complex equipment. This prototype device has great potential for use in the semi-quantitative and qualitative identification of pathogens in on-site primary diagnoses." @default.
- W3080931063 created "2020-09-01" @default.
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- W3080931063 date "2020-01-01" @default.
- W3080931063 modified "2023-10-14" @default.
- W3080931063 title "Development of a portable lab-on-a-valve device for making primary diagnoses based on gold-nanoparticle aggregation induced by a switchable linker" @default.
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- W3080931063 doi "https://doi.org/10.1039/d0ra05115b" @default.
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