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- W3080965807 abstract "There are limited proven therapeutic options for the prevention and treatment of COVID-19. The role of vitamin and mineral supplementation or immunonutrition has previously been explored in a number of clinical trials in intensive care settings, and there are several hypotheses to support their routine use. The aim of this narrative review was to investigate whether vitamin supplementation is beneficial in COVID-19. A systematic search strategy with a narrative literature summary was designed, using the Medline, EMBASE, Cochrane Trials Register, WHO International Clinical Trial Registry, and Nexis media databases. The immune-mediating, antioxidant and antimicrobial roles of vitamins A to E were explored and their potential role in the fight against COVID-19 was evaluated. The major topics extracted for narrative synthesis were physiological and immunological roles of each vitamin, their role in respiratory infections, acute respiratory distress syndrome (ARDS), and COVID-19. Vitamins A to E highlighted potentially beneficial roles in the fight against COVID-19 via antioxidant effects, immunomodulation, enhancing natural barriers, and local paracrine signaling. Level 1 and 2 evidence supports the use of thiamine, vitamin C, and vitamin D in COVID-like respiratory diseases, ARDS, and sepsis. Although there are currently no published clinical trials due to the novelty of SARS-CoV-2 infection, there is pathophysiologic rationale for exploring the use of vitamins in this global pandemic, supported by early anecdotal reports from international groups. The final outcomes of ongoing trials of vitamin supplementation are awaited with interest." @default.
- W3080965807 created "2020-09-01" @default.
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- W3080965807 date "2020-08-23" @default.
- W3080965807 modified "2023-10-14" @default.
- W3080965807 title "Could Vitamins Help in the Fight Against COVID-19?" @default.
- W3080965807 cites W1224318197 @default.
- W3080965807 cites W1506169385 @default.
- W3080965807 cites W1527288304 @default.
- W3080965807 cites W1546629881 @default.
- W3080965807 cites W1551028857 @default.
- W3080965807 cites W1564211606 @default.
- W3080965807 cites W1595363731 @default.
- W3080965807 cites W1600560134 @default.
- W3080965807 cites W1645379154 @default.
- W3080965807 cites W1676039051 @default.
- W3080965807 cites W1773795678 @default.
- W3080965807 cites W1866685620 @default.
- W3080965807 cites W1881396261 @default.
- W3080965807 cites W1885640498 @default.
- W3080965807 cites W1964982019 @default.
- W3080965807 cites W1965843068 @default.
- W3080965807 cites W1969796512 @default.
- W3080965807 cites W1976776496 @default.
- W3080965807 cites W1978153426 @default.
- W3080965807 cites W1978407431 @default.
- W3080965807 cites W1981160854 @default.
- W3080965807 cites W1985802554 @default.
- W3080965807 cites W1988327094 @default.
- W3080965807 cites W1988893380 @default.
- W3080965807 cites W1996143998 @default.
- W3080965807 cites W1996351596 @default.
- W3080965807 cites W1998724120 @default.
- W3080965807 cites W2000164041 @default.
- W3080965807 cites W2004136613 @default.
- W3080965807 cites W2005457704 @default.
- W3080965807 cites W2007196081 @default.
- W3080965807 cites W2009697420 @default.
- W3080965807 cites W2011296521 @default.
- W3080965807 cites W2013292958 @default.
- W3080965807 cites W2015348320 @default.
- W3080965807 cites W2018263946 @default.
- W3080965807 cites W2019489183 @default.
- W3080965807 cites W2021077316 @default.
- W3080965807 cites W2025337318 @default.
- W3080965807 cites W2025830885 @default.
- W3080965807 cites W2026131789 @default.
- W3080965807 cites W2030660084 @default.
- W3080965807 cites W2037106653 @default.
- W3080965807 cites W2037745280 @default.
- W3080965807 cites W2051707833 @default.
- W3080965807 cites W2053885482 @default.
- W3080965807 cites W2056187305 @default.
- W3080965807 cites W2058570017 @default.
- W3080965807 cites W2062526133 @default.
- W3080965807 cites W2064460451 @default.
- W3080965807 cites W2067940396 @default.
- W3080965807 cites W2070603331 @default.
- W3080965807 cites W2071622038 @default.
- W3080965807 cites W2073143472 @default.
- W3080965807 cites W2074748031 @default.
- W3080965807 cites W2074869909 @default.
- W3080965807 cites W2076111774 @default.
- W3080965807 cites W2078643271 @default.
- W3080965807 cites W2079369349 @default.
- W3080965807 cites W2079496053 @default.
- W3080965807 cites W2080196545 @default.
- W3080965807 cites W2082548756 @default.
- W3080965807 cites W2083245140 @default.
- W3080965807 cites W2083631490 @default.
- W3080965807 cites W2086169535 @default.
- W3080965807 cites W2088985415 @default.
- W3080965807 cites W2090512867 @default.
- W3080965807 cites W2090575998 @default.
- W3080965807 cites W2093540512 @default.
- W3080965807 cites W2094694215 @default.
- W3080965807 cites W2095836198 @default.
- W3080965807 cites W2096678608 @default.
- W3080965807 cites W2097784085 @default.
- W3080965807 cites W2099216315 @default.
- W3080965807 cites W2101787166 @default.
- W3080965807 cites W2104934425 @default.
- W3080965807 cites W2105482874 @default.
- W3080965807 cites W2106425862 @default.
- W3080965807 cites W2108345886 @default.
- W3080965807 cites W2112782415 @default.
- W3080965807 cites W2113607278 @default.
- W3080965807 cites W2113801461 @default.
- W3080965807 cites W2119410610 @default.
- W3080965807 cites W2121184260 @default.