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- W3081020635 endingPage "32" @default.
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- W3081020635 abstract ": There are several esophageal disorders that can occur in the pediatric population. Eosinophilic esophagitis (EoE) is an eosinophil predominant inflammatory disease of the esophagus that was first characterized in the early 1900’s. EoE is the most common pediatric esophageal inflammatory condition after gastroesophageal reflux disease (GERD). Longstanding GERD is a known risk factor for the development of Barrett’s esophagus (BE) in both children and adults. BE is associated with the development of dysplasia and, if left undiagnosed, may progress to the development of esophageal adenocarcinoma (EAC). EAC and esophageal squamous cell carcinoma (ESCC) comprise the majority of childhood esophageal malignant neoplasms. The prevalence of EoE continues to rise within the pediatric population. On the other hand, both BE and esophageal neoplasms remain extremely rare in children. The relationship between a chronic inflammatory condition like EoE to BE and/or esophageal neoplasms remains unclear. The current research of these disease entities is prioritized to further understanding the disease pathogenesis and disease progression, exploring new diagnostic modalities, and developing novel treatments or less invasive therapeutic options. The focus of the following narrative review is to provide a summary of the current clinical practices, future research and their implications on these various esophageal disorders." @default.
- W3081020635 created "2020-09-01" @default.
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- W3081020635 creator A5090766228 @default.
- W3081020635 date "2021-07-01" @default.
- W3081020635 modified "2023-10-15" @default.
- W3081020635 title "Eosinophilic esophagitis, Barrett’s esophagus and esophageal neoplasms in the pediatric patient: a narrative review" @default.
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- W3081020635 doi "https://doi.org/10.21037/tgh-20-223" @default.
- W3081020635 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8343421" @default.
- W3081020635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34423153" @default.