Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081236114> ?p ?o ?g. }
- W3081236114 abstract "Group B Streptococcus (GBS) meningitis remains a major cause of poor health outcomes very early in life. Both the host-pathogen relationship leading to disease and the massive host response to infection contributing to these poor outcomes are orchestrated at the tissue and cell type levels. GBS meningitis is thought to result when bacteria present in the blood circumvent the selectively permeable vascular barriers that feed the brain. Additionally, tissue damage subsequent to bacterial invasion is mediated by inflammation and by immune cells from the periphery crossing the blood-brain barrier. Indeed, the vasculature plays a central role in disease processes occurring during GBS infection of the brain. Here, we employed quantitative proteomic analysis of brain vascular substructures during invasive GBS disease. We used the generated data to map molecular alterations associated with tissue perturbation, finding widespread intracellular dysfunction and punctuating the importance of investigations relegated to tissue type over the whole organ." @default.
- W3081236114 created "2020-09-01" @default.
- W3081236114 creator A5003833573 @default.
- W3081236114 creator A5006079772 @default.
- W3081236114 creator A5007767031 @default.
- W3081236114 creator A5009651541 @default.
- W3081236114 creator A5029511959 @default.
- W3081236114 creator A5030470781 @default.
- W3081236114 creator A5032562567 @default.
- W3081236114 creator A5042931548 @default.
- W3081236114 creator A5044849370 @default.
- W3081236114 creator A5053621678 @default.
- W3081236114 creator A5056550275 @default.
- W3081236114 creator A5067852918 @default.
- W3081236114 creator A5068969129 @default.
- W3081236114 creator A5082564115 @default.
- W3081236114 date "2020-08-25" @default.
- W3081236114 modified "2023-10-13" @default.
- W3081236114 title "Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B <i>Streptococcus</i>" @default.
- W3081236114 cites W1495151309 @default.
- W3081236114 cites W1501334428 @default.
- W3081236114 cites W1532860571 @default.
- W3081236114 cites W1575681972 @default.
- W3081236114 cites W1903546212 @default.
- W3081236114 cites W1941687931 @default.
- W3081236114 cites W1975936189 @default.
- W3081236114 cites W1986962675 @default.
- W3081236114 cites W1988146323 @default.
- W3081236114 cites W1989277387 @default.
- W3081236114 cites W1997334188 @default.
- W3081236114 cites W1998143889 @default.
- W3081236114 cites W2006986579 @default.
- W3081236114 cites W2017713208 @default.
- W3081236114 cites W2025658823 @default.
- W3081236114 cites W2029531605 @default.
- W3081236114 cites W2029987970 @default.
- W3081236114 cites W2048280438 @default.
- W3081236114 cites W2051768294 @default.
- W3081236114 cites W2058821806 @default.
- W3081236114 cites W2062422359 @default.
- W3081236114 cites W2067056774 @default.
- W3081236114 cites W2067301876 @default.
- W3081236114 cites W2084123893 @default.
- W3081236114 cites W2090169073 @default.
- W3081236114 cites W2091650109 @default.
- W3081236114 cites W2096057003 @default.
- W3081236114 cites W2101634685 @default.
- W3081236114 cites W2103296967 @default.
- W3081236114 cites W2110438218 @default.
- W3081236114 cites W2123886946 @default.
- W3081236114 cites W2127690345 @default.
- W3081236114 cites W2130850760 @default.
- W3081236114 cites W2130962254 @default.
- W3081236114 cites W2136487679 @default.
- W3081236114 cites W2141369179 @default.
- W3081236114 cites W2146413343 @default.
- W3081236114 cites W2146582952 @default.
- W3081236114 cites W2146811846 @default.
- W3081236114 cites W2148309708 @default.
- W3081236114 cites W2152430077 @default.
- W3081236114 cites W2153132589 @default.
- W3081236114 cites W2161950146 @default.
- W3081236114 cites W2162580275 @default.
- W3081236114 cites W2181248553 @default.
- W3081236114 cites W2316957167 @default.
- W3081236114 cites W2337350743 @default.
- W3081236114 cites W2337369609 @default.
- W3081236114 cites W2338225276 @default.
- W3081236114 cites W2338615663 @default.
- W3081236114 cites W2514206815 @default.
- W3081236114 cites W2619060418 @default.
- W3081236114 cites W2765950493 @default.
- W3081236114 cites W2795350876 @default.
- W3081236114 cites W2797100117 @default.
- W3081236114 cites W2801287725 @default.
- W3081236114 cites W2887374204 @default.
- W3081236114 cites W2896013426 @default.
- W3081236114 cites W2902032664 @default.
- W3081236114 cites W2969531189 @default.
- W3081236114 cites W2979370432 @default.
- W3081236114 cites W4231254854 @default.
- W3081236114 cites W4233838756 @default.
- W3081236114 cites W4313335109 @default.
- W3081236114 cites W80072382 @default.
- W3081236114 doi "https://doi.org/10.1128/msystems.00368-20" @default.
- W3081236114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7449606" @default.
- W3081236114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32843537" @default.
- W3081236114 hasPublicationYear "2020" @default.
- W3081236114 type Work @default.
- W3081236114 sameAs 3081236114 @default.
- W3081236114 citedByCount "6" @default.
- W3081236114 countsByYear W30812361142021 @default.
- W3081236114 countsByYear W30812361142022 @default.
- W3081236114 countsByYear W30812361142023 @default.
- W3081236114 crossrefType "journal-article" @default.
- W3081236114 hasAuthorship W3081236114A5003833573 @default.
- W3081236114 hasAuthorship W3081236114A5006079772 @default.
- W3081236114 hasAuthorship W3081236114A5007767031 @default.
- W3081236114 hasAuthorship W3081236114A5009651541 @default.
- W3081236114 hasAuthorship W3081236114A5029511959 @default.