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• W3081285213 abstract "Chromatin Conformation Capture techniques have unveiled several layers of chromosome organization such as the segregation in compartments, the folding in topologically associating domains (TADs), and site-specific looping interactions. The discovery of this genome hierarchical organization emerged from the computational analysis of chromatin capture data. With the increasing availability of such data, automatic pipelines for the robust comparison, grouping, and classification of multiple experiments are needed. Here we present a pipeline based on the TADbit framework that emphasizes reproducibility, automation, quality check, and statistical robustness. This comprehensive modular pipeline covers all the steps from the sequencing products to the visualization of reconstructed 3D models of the chromatin." @default.
• W3081285213 created "2020-09-01" @default.
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• W3081285213 date "2020-08-21" @default.
• W3081285213 modified "2023-10-18" @default.
• W3081285213 title "Analysis, Modeling, and Visualization of Chromosome Conformation Capture Experiments" @default.
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• W3081285213 doi "https://doi.org/10.1007/978-1-0716-0664-3_4" @default.
• W3081285213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32820398" @default.
• W3081285213 hasPublicationYear "2020" @default.
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