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- W3081330517 abstract "Antimicrobial poly(vinyl alcohol) (PVA) hydrogels attracted much attentions in the last decade. In this work, a novel antimicrobial PVA hydrogel was prepared through compounding PVA with polyhexamethylene guanidine hydrochloride (PHMG) and freezing‐thawing method. These composite hydrogels behaved above 99.9% of antimicrobial rates against both Escherichia coli and Staphylococcus aureus even at 0.003 wt% of PHMG, and the nonleaching characteristic of PHMG as well as long‐acting antimicrobial activities. The PVA/0.100 wt% PHMG hydrogel had 120% higher tensile strength than pure PVA hydrogel, and its water vapor transmission rate was 4530 ± 245 g/m 2 /d, which was at an optimal range for injured skin (279‐5138 g/m 2 /d). This work provides a simple approach to develop nonleaching antimicrobial PVA hydrogels with extremely few PHMG for wound dressing and other potential applications in biomedical field." @default.
- W3081330517 created "2020-09-01" @default.
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- W3081330517 date "2020-08-21" @default.
- W3081330517 modified "2023-09-26" @default.
- W3081330517 title "Nonleaching antimicrobial poly(vinyl alcohol)/polyhexamethylene guanidine hydrochloride hydrogels reinforced by hydrogen bond" @default.
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- W3081330517 doi "https://doi.org/10.1002/pat.5048" @default.
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