FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081553018> ?p ?o ?g. }

• W3081553018 abstract "Introduction Dual-task walking is common in daily life, but becomes more difficult with aging. Little is known about the neurobiological mechanisms in the brain affecting competing cognitive demands. Translational studies with human and animal models are needed to address this gap. This pilot study investigates the feasibility of implementing a novel cross-species dual-task model in humans and rats, and seeks to establish preliminary evidence that the model induces a dual-task cost. Methods Young and older humans and rats performed an object discrimination task (OD), a baseline task of typical walking (baseline), an alternation turning task on a Figure-8 walking course (Alt), and a dual-task combining object discrimination with the alternation task (AltOD). Primary behavioral assessments including walking speed and correct selections for object discrimination and turning direction. In humans, left prefrontal cortex activity was measured with functional near infrared spectroscopy (fNIRS). Results Human subjects generally performed well on all tasks, but the older adults exhibited a trend for slowing of walking speed immediately prior to the turning decision for Alt and AltOD compared to baseline. Older adults also had heightened prefrontal activity relative to young adults for the Alt and AltOD tasks. Older rodents required more training than young rodents to learn the alternations task. When tested on AltOD with and without a 15-second delay between trials, older rodents exhibited a substantial performance deficit for the delayed version on the initial day of testing. Discussion This study demonstrates feasibility in implementing a cross-species dual-task model, and preliminary evidence of dual-task cost in both humans and rats. The magnitude of effects were small, likely due to the high functional status of both older humans and rats, as well as the relative ease of each task. Future versions of this test should make the tasks more challenging." @default.
• W3081553018 created "2020-09-08" @default.
• W3081553018 creator A5010600781 @default.
• W3081553018 creator A5020062882 @default.
• W3081553018 creator A5021110898 @default.
• W3081553018 creator A5054179109 @default.
• W3081553018 creator A5065210512 @default.
• W3081553018 creator A5071496556 @default.
• W3081553018 date "2020-09-02" @default.
• W3081553018 modified "2023-10-14" @default.
• W3081553018 title "A Cross-species Model of Dual-Task Walking in Young and Older Humans and Rats" @default.
• W3081553018 cites W1593904343 @default.
• W3081553018 cites W1607330615 @default.
• W3081553018 cites W1780106974 @default.
• W3081553018 cites W1817525470 @default.
• W3081553018 cites W191426077 @default.
• W3081553018 cites W1967333153 @default.
• W3081553018 cites W1973311433 @default.
• W3081553018 cites W1987023949 @default.
• W3081553018 cites W1990040655 @default.
• W3081553018 cites W1999027550 @default.
• W3081553018 cites W2000053231 @default.
• W3081553018 cites W2001189179 @default.
• W3081553018 cites W2009074334 @default.
• W3081553018 cites W2010853947 @default.
• W3081553018 cites W2013468866 @default.
• W3081553018 cites W2019249853 @default.
• W3081553018 cites W2022686017 @default.
• W3081553018 cites W2023209728 @default.
• W3081553018 cites W2032384497 @default.
• W3081553018 cites W2034185215 @default.
• W3081553018 cites W2044323113 @default.
• W3081553018 cites W2069776467 @default.
• W3081553018 cites W2075981634 @default.
• W3081553018 cites W2077711513 @default.
• W3081553018 cites W2089725106 @default.
• W3081553018 cites W2101049534 @default.
• W3081553018 cites W2102483455 @default.
• W3081553018 cites W2103861118 @default.
• W3081553018 cites W2130296687 @default.
• W3081553018 cites W2131864009 @default.
• W3081553018 cites W2132122905 @default.
• W3081553018 cites W2145107163 @default.
• W3081553018 cites W2147303187 @default.
• W3081553018 cites W2165201535 @default.
• W3081553018 cites W2166248226 @default.
• W3081553018 cites W2201919114 @default.
• W3081553018 cites W2396715641 @default.
• W3081553018 cites W2432952663 @default.
• W3081553018 cites W2471480526 @default.
• W3081553018 cites W2593274727 @default.
• W3081553018 cites W2599564137 @default.
• W3081553018 cites W2626830376 @default.
• W3081553018 cites W2736858636 @default.
• W3081553018 cites W2749672090 @default.
• W3081553018 cites W2764315683 @default.
• W3081553018 cites W2794995210 @default.
• W3081553018 cites W2810783283 @default.
• W3081553018 cites W2881486088 @default.
• W3081553018 cites W2902605370 @default.
• W3081553018 cites W2996879041 @default.
• W3081553018 cites W3002738480 @default.
• W3081553018 cites W3003484986 @default.
• W3081553018 cites W3008821956 @default.
• W3081553018 cites W3022000657 @default.
• W3081553018 cites W4250265752 @default.
• W3081553018 doi "https://doi.org/10.3389/fnagi.2020.00276" @default.
• W3081553018 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7492995" @default.
• W3081553018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32982717" @default.
• W3081553018 hasPublicationYear "2020" @default.
• W3081553018 type Work @default.
• W3081553018 sameAs 3081553018 @default.
• W3081553018 citedByCount "5" @default.
• W3081553018 countsByYear W30815530182021 @default.
• W3081553018 countsByYear W30815530182022 @default.
• W3081553018 countsByYear W30815530182023 @default.
• W3081553018 crossrefType "journal-article" @default.
• W3081553018 hasAuthorship W3081553018A5010600781 @default.
• W3081553018 hasAuthorship W3081553018A5020062882 @default.
• W3081553018 hasAuthorship W3081553018A5021110898 @default.
• W3081553018 hasAuthorship W3081553018A5054179109 @default.
• W3081553018 hasAuthorship W3081553018A5065210512 @default.
• W3081553018 hasAuthorship W3081553018A5071496556 @default.
• W3081553018 hasBestOaLocation W30815530181 @default.
• W3081553018 hasConcept C124952713 @default.
• W3081553018 hasConcept C138885662 @default.
• W3081553018 hasConcept C142362112 @default.
• W3081553018 hasConcept C15744967 @default.
• W3081553018 hasConcept C162324750 @default.
• W3081553018 hasConcept C169760540 @default.
• W3081553018 hasConcept C169900460 @default.
• W3081553018 hasConcept C180747234 @default.
• W3081553018 hasConcept C187736073 @default.
• W3081553018 hasConcept C26826806 @default.
• W3081553018 hasConcept C2780451532 @default.
• W3081553018 hasConcept C2780980858 @default.
• W3081553018 hasConcept C2781195155 @default.
• W3081553018 hasConcept C41895202 @default.
• W3081553018 hasConcept C548259974 @default.
• W3081553018 hasConcept C71924100 @default.

• next