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- W3081596587 abstract "Zebrafish are an excellent model organism to study many aspects of vertebrate sensory encoding and behavior. Their escape responses begin with a C-shaped body bend followed by several swimming bouts away from the potentially threatening stimulus. This highly stereotyped motor behavior provides a model for studying startle reflexes and the neural circuitry underlying multisensory encoding and locomotion. Channelrhodopsin (ChR2) can be expressed in the lateral line and ear hair cells of zebrafish and can be excited in vivo to elicit these rapid forms of escape. Here we review our methods for studying transgenic ChR2-expressing zebrafish larvae, including screening for positive expression of ChR2 and recording field potentials and high-speed videos of optically evoked escape responses. We also highlight important features of the acquired data and provide a brief review of other zebrafish research that utilizes or has the potential to benefit from ChR2 and optogenetics." @default.
- W3081596587 created "2020-09-08" @default.
- W3081596587 creator A5037020191 @default.
- W3081596587 creator A5050829510 @default.
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- W3081596587 creator A5078528240 @default.
- W3081596587 creator A5086549381 @default.
- W3081596587 creator A5091262712 @default.
- W3081596587 date "2020-09-01" @default.
- W3081596587 modified "2023-10-06" @default.
- W3081596587 title "Recording Channelrhodopsin-Evoked Field Potentials and Startle Responses from Larval Zebrafish" @default.
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