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- W3081639489 abstract "Abstract Vitamin D overdosing includes hypercalcemia, hypercalciuria, and mineral deposits in soft tissues. A safety upper limit of 4000 IU/day, which is consistently accepted, has been challenged, since the risk of adverse events in other systems than calcium-phosphate homeostasis may depend not only on the dose, but on the outcome, the treatment regimen, and possibly the age, sex and vitamin D status. The therapeutic window of vitamin D supplementation may be narrower than hitherto recognized. The prevention and/or correction of vitamin D deficiency/insufficiency with 800–1000 IU/daily of vitamin D or 10 µg/day of calcifediol are safe. Because of their potential harm, larger doses given on the long term or in intermittent regimens should not be selected." @default.
- W3081639489 created "2020-09-08" @default.
- W3081639489 creator A5082866696 @default.
- W3081639489 date "2020-08-28" @default.
- W3081639489 modified "2023-10-10" @default.
- W3081639489 title "Vitamin D supplementation: upper limit for safety revisited?" @default.
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- W3081639489 doi "https://doi.org/10.1007/s40520-020-01678-x" @default.
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