FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081665544> ?p ?o ?g. }

• W3081665544 abstract "BACKGROUND. Determining the pathogenetic mechanisms of small-caliber renal artery remodeling in chronic glomerulone­phritis (GN) is an urgent task of nephrology, the implementation of which will allow establishing new diagnostic and therapeutic approaches to patients management. THE AIM: To evaluate the influence of hemodynamic, tubulointerstitial, and endothe- liotropic risk factors on the probability of remodeling of interlobular arteries in an experimental model of glomerulonephritis. MATERIALS AND METHODS. The experiment included 45 individuals of white mongrel rats, 3 of which were used to prepare an antigen suspension (AS), and 42 rats were divided into 4 groups: 9 individuals in the main groups (with the introduction of only AS, with the introduction of an incomplete Freund adjuvant, with AS and sodium chloride, with AS and perindopril) and 6 ratsin the control group. Glomerulonephritis was formed in the main groups of the experiment. Systolic blood pressure (SAD), the protein level in the urine, and the presence of edematous syndrome were monitored initially, on the 15th, 30th, and 60th day of the experiment. The size of the interlobular artery (MA) was determined by the morphological study, and the expression of VEGF and TGFp in the kidneys. RESULTS. Morphological signs of glomerulonephritis were obtained in all the main groups of the experiment as early as day 15. The greatest increase in SAD, protein in the urine, the presence of edematous syndrome in groups with the introduction of AS and AS with sodium chloride was found. The highest expression of VEGF and TGFp was found in these groups of rats. In the group with AS with perindopril, normotension was formed, the protein level was lower than in rats with AS with or without the use of sodium chloride, and there was no edematous syndrome. The expression of VEGF and TGFp was minimal. Interlobular artery remodeling in established groups of AS an AC with sodium chloride. In the remain­ing groups of rats, the size of the interlobular arteries was comparable to the control group. CONCLUSION. The leading role of systemic blood pressure in the remodeling of small-diameter kidney arteries in glomerulonephritis has been established. Despite the presence of active glomerulonephritis in rats, the structure of small arteries does not change during the formation of normotension." @default.
• W3081665544 created "2020-09-08" @default.
• W3081665544 creator A5015682374 @default.
• W3081665544 creator A5028465599 @default.
• W3081665544 creator A5041321398 @default.
• W3081665544 creator A5048895689 @default.
• W3081665544 creator A5058271496 @default.
• W3081665544 creator A5072275737 @default.
• W3081665544 creator A5090517012 @default.
• W3081665544 creator A5090717625 @default.
• W3081665544 date "2020-08-31" @default.
• W3081665544 modified "2023-09-27" @default.
• W3081665544 title "Prediction of remodeling of small diameter arteries in the model of experimental glomerulonephritis" @default.
• W3081665544 cites W2588851854 @default.
• W3081665544 cites W2897831261 @default.
• W3081665544 cites W2898113161 @default.
• W3081665544 cites W2900020463 @default.
• W3081665544 cites W2952749964 @default.
• W3081665544 cites W2998941099 @default.
• W3081665544 cites W4247531028 @default.
• W3081665544 doi "https://doi.org/10.36485/1561-6274-2020-24-5-64-71" @default.
• W3081665544 hasPublicationYear "2020" @default.
• W3081665544 type Work @default.
• W3081665544 sameAs 3081665544 @default.
• W3081665544 citedByCount "0" @default.
• W3081665544 crossrefType "journal-article" @default.
• W3081665544 hasAuthorship W3081665544A5015682374 @default.
• W3081665544 hasAuthorship W3081665544A5028465599 @default.
• W3081665544 hasAuthorship W3081665544A5041321398 @default.
• W3081665544 hasAuthorship W3081665544A5048895689 @default.
• W3081665544 hasAuthorship W3081665544A5058271496 @default.
• W3081665544 hasAuthorship W3081665544A5072275737 @default.
• W3081665544 hasAuthorship W3081665544A5090517012 @default.
• W3081665544 hasAuthorship W3081665544A5090717625 @default.
• W3081665544 hasConcept C126322002 @default.
• W3081665544 hasConcept C142724271 @default.
• W3081665544 hasConcept C164705383 @default.
• W3081665544 hasConcept C2776634560 @default.
• W3081665544 hasConcept C2780026642 @default.
• W3081665544 hasConcept C2780091579 @default.
• W3081665544 hasConcept C2780368995 @default.
• W3081665544 hasConcept C71924100 @default.
• W3081665544 hasConcept C84393581 @default.
• W3081665544 hasConceptScore W3081665544C126322002 @default.
• W3081665544 hasConceptScore W3081665544C142724271 @default.
• W3081665544 hasConceptScore W3081665544C164705383 @default.
• W3081665544 hasConceptScore W3081665544C2776634560 @default.
• W3081665544 hasConceptScore W3081665544C2780026642 @default.
• W3081665544 hasConceptScore W3081665544C2780091579 @default.
• W3081665544 hasConceptScore W3081665544C2780368995 @default.
• W3081665544 hasConceptScore W3081665544C71924100 @default.
• W3081665544 hasConceptScore W3081665544C84393581 @default.
• W3081665544 hasLocation W30816655441 @default.
• W3081665544 hasOpenAccess W3081665544 @default.
• W3081665544 hasPrimaryLocation W30816655441 @default.
• W3081665544 hasRelatedWork W10060292 @default.
• W3081665544 hasRelatedWork W12547131 @default.
• W3081665544 hasRelatedWork W12877399 @default.
• W3081665544 hasRelatedWork W13518585 @default.
• W3081665544 hasRelatedWork W15264300 @default.
• W3081665544 hasRelatedWork W15326854 @default.
• W3081665544 hasRelatedWork W2112058 @default.
• W3081665544 hasRelatedWork W2842080 @default.
• W3081665544 hasRelatedWork W5399251 @default.
• W3081665544 hasRelatedWork W9147909 @default.
• W3081665544 isParatext "false" @default.
• W3081665544 isRetracted "false" @default.
• W3081665544 magId "3081665544" @default.
• W3081665544 workType "article" @default.