Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081753227> ?p ?o ?g. }
- W3081753227 endingPage "1190" @default.
- W3081753227 startingPage "1172" @default.
- W3081753227 abstract "Fungal immunomodulatory proteins (FIPs) are fascinating small and heat-stable bioactive proteins in a distinct protein family due to similarities in their structures and sequences. They are found in fungi, including the fruiting bodies producing fungi comprised of culinary and medicinal mushrooms. Structurally, most FIPs exist as homodimers; each subunit consisting of an N-terminal α-helix dimerization and a C-terminal fibronectin III domain. Increasing numbers of identified FIPs from either different or same fungal species clearly indicates the growing research interests into its medicinal properties which include immunomodulatory, anti-inflammation, anti-allergy, and anticancer. Most FIPs increased IFN-γ production in peripheral blood mononuclear cells, potentially exerting immunomodulatory and anti-inflammatory effects by inhibiting overproduction of T helper-2 (Th2) cytokines common in an allergy reaction. Recently, FIP from Ganoderma microsporum (FIP-gmi) was shown to promote neurite outgrowth for potential therapeutic applications in neuro-disorders. This review discussed FIPs’ structural and protein characteristics, their recombinant protein production for functional studies, and the recent advances in their development and applications as pharmaceutics and functional foods." @default.
- W3081753227 created "2020-09-08" @default.
- W3081753227 creator A5014395146 @default.
- W3081753227 creator A5055019724 @default.
- W3081753227 creator A5077718813 @default.
- W3081753227 creator A5079798558 @default.
- W3081753227 date "2020-08-28" @default.
- W3081753227 modified "2023-10-02" @default.
- W3081753227 title "New advances and potentials of fungal immunomodulatory proteins for therapeutic purposes" @default.
- W3081753227 cites W1501714393 @default.
- W3081753227 cites W1594779960 @default.
- W3081753227 cites W1888665141 @default.
- W3081753227 cites W1928236782 @default.
- W3081753227 cites W1964242138 @default.
- W3081753227 cites W1966649995 @default.
- W3081753227 cites W1967464998 @default.
- W3081753227 cites W1969350938 @default.
- W3081753227 cites W1970113458 @default.
- W3081753227 cites W1971095506 @default.
- W3081753227 cites W1974930528 @default.
- W3081753227 cites W1975665552 @default.
- W3081753227 cites W1976777085 @default.
- W3081753227 cites W1978646727 @default.
- W3081753227 cites W1981192363 @default.
- W3081753227 cites W1982715566 @default.
- W3081753227 cites W1985383147 @default.
- W3081753227 cites W1986755395 @default.
- W3081753227 cites W1989090634 @default.
- W3081753227 cites W1989789071 @default.
- W3081753227 cites W1994329231 @default.
- W3081753227 cites W1994909851 @default.
- W3081753227 cites W1996780872 @default.
- W3081753227 cites W1997008111 @default.
- W3081753227 cites W2005539993 @default.
- W3081753227 cites W2007610616 @default.
- W3081753227 cites W2010293066 @default.
- W3081753227 cites W2010588708 @default.
- W3081753227 cites W2016914938 @default.
- W3081753227 cites W2017629228 @default.
- W3081753227 cites W2019703065 @default.
- W3081753227 cites W2022165024 @default.
- W3081753227 cites W2022248228 @default.
- W3081753227 cites W2024152447 @default.
- W3081753227 cites W2027836693 @default.
- W3081753227 cites W2028230977 @default.
- W3081753227 cites W2034969165 @default.
- W3081753227 cites W2047731143 @default.
- W3081753227 cites W2048689588 @default.
- W3081753227 cites W2053397166 @default.
- W3081753227 cites W2053798662 @default.
- W3081753227 cites W2055825936 @default.
- W3081753227 cites W2064610607 @default.
- W3081753227 cites W2065266111 @default.
- W3081753227 cites W2065687338 @default.
- W3081753227 cites W2066846431 @default.
- W3081753227 cites W2068122784 @default.
- W3081753227 cites W2070145406 @default.
- W3081753227 cites W2079473304 @default.
- W3081753227 cites W2079517529 @default.
- W3081753227 cites W2079590084 @default.
- W3081753227 cites W2082581989 @default.
- W3081753227 cites W2082658201 @default.
- W3081753227 cites W2086775232 @default.
- W3081753227 cites W2091258609 @default.
- W3081753227 cites W2094219438 @default.
- W3081753227 cites W2097951030 @default.
- W3081753227 cites W2102952752 @default.
- W3081753227 cites W2106586933 @default.
- W3081753227 cites W2112683779 @default.
- W3081753227 cites W2114077388 @default.
- W3081753227 cites W2130401538 @default.
- W3081753227 cites W2135780793 @default.
- W3081753227 cites W2141254530 @default.
- W3081753227 cites W2152467765 @default.
- W3081753227 cites W2157973267 @default.
- W3081753227 cites W2168307472 @default.
- W3081753227 cites W2299486975 @default.
- W3081753227 cites W2308670129 @default.
- W3081753227 cites W2322825412 @default.
- W3081753227 cites W2490364301 @default.
- W3081753227 cites W2508972830 @default.
- W3081753227 cites W2522169390 @default.
- W3081753227 cites W2524169008 @default.
- W3081753227 cites W2564022399 @default.
- W3081753227 cites W2587800094 @default.
- W3081753227 cites W2604431044 @default.
- W3081753227 cites W2624433117 @default.
- W3081753227 cites W2786141949 @default.
- W3081753227 cites W2799279104 @default.
- W3081753227 cites W2892726955 @default.
- W3081753227 cites W2898879588 @default.
- W3081753227 cites W2900965093 @default.
- W3081753227 cites W2905377012 @default.
- W3081753227 cites W2921661270 @default.
- W3081753227 cites W2936176174 @default.
- W3081753227 cites W2944207476 @default.
- W3081753227 cites W2989294612 @default.
- W3081753227 cites W3042198092 @default.