Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081803629> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3081803629 endingPage "169" @default.
- W3081803629 startingPage "151" @default.
- W3081803629 abstract "The delivery of cells into damaged myocardium induces limited cardiac regeneration due to extensive cell death. In an effort to limit cell death, our lab formulates three-dimensional matrices as a delivery system for cell therapy. Our primary work has been focused on the formation of engineered cardiac tissues (ECTs) from human-induced pluripotent stem cell-derived engineered cardiac cells. However, ECT immaturity hinders ability to fully recover damaged myocardium. Various conditioning regimens such as mechanical stretch and/or electric pacing have been used to activate maturation pathways. To improve ECT maturity, we use non-contacting chronic light stimulation using heterologously expressed light-sensitive channelrhodopsin ion channels. We transduce ECTs with an AAV packaged channelrhodopsin and chronically optically pace (C-OP) ECTs for 1 week above the intrinsic beat rate, resulting in increased ECT electrophysiological properties." @default.
- W3081803629 created "2020-09-08" @default.
- W3081803629 creator A5018745891 @default.
- W3081803629 creator A5035391460 @default.
- W3081803629 creator A5058468432 @default.
- W3081803629 creator A5064932206 @default.
- W3081803629 creator A5075623873 @default.
- W3081803629 date "2020-09-01" @default.
- W3081803629 modified "2023-10-03" @default.
- W3081803629 title "Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues" @default.
- W3081803629 cites W1902126572 @default.
- W3081803629 cites W1975574255 @default.
- W3081803629 cites W1978253480 @default.
- W3081803629 cites W1979694957 @default.
- W3081803629 cites W2001406655 @default.
- W3081803629 cites W2035312069 @default.
- W3081803629 cites W2050783691 @default.
- W3081803629 cites W2062145052 @default.
- W3081803629 cites W2094280614 @default.
- W3081803629 cites W2096237299 @default.
- W3081803629 cites W2097441795 @default.
- W3081803629 cites W2101038486 @default.
- W3081803629 cites W2116111212 @default.
- W3081803629 cites W2116744112 @default.
- W3081803629 cites W2120473106 @default.
- W3081803629 cites W2145306368 @default.
- W3081803629 cites W2160772892 @default.
- W3081803629 cites W2295212086 @default.
- W3081803629 cites W2502708568 @default.
- W3081803629 cites W2604927641 @default.
- W3081803629 cites W2950445819 @default.
- W3081803629 cites W4210574564 @default.
- W3081803629 doi "https://doi.org/10.1007/978-1-0716-0830-2_10" @default.
- W3081803629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32865744" @default.
- W3081803629 hasPublicationYear "2020" @default.
- W3081803629 type Work @default.
- W3081803629 sameAs 3081803629 @default.
- W3081803629 citedByCount "3" @default.
- W3081803629 countsByYear W30818036292021 @default.
- W3081803629 countsByYear W30818036292022 @default.
- W3081803629 countsByYear W30818036292023 @default.
- W3081803629 crossrefType "book-chapter" @default.
- W3081803629 hasAuthorship W3081803629A5018745891 @default.
- W3081803629 hasAuthorship W3081803629A5035391460 @default.
- W3081803629 hasAuthorship W3081803629A5058468432 @default.
- W3081803629 hasAuthorship W3081803629A5064932206 @default.
- W3081803629 hasAuthorship W3081803629A5075623873 @default.
- W3081803629 hasConcept C104317684 @default.
- W3081803629 hasConcept C107459253 @default.
- W3081803629 hasConcept C145103041 @default.
- W3081803629 hasConcept C1491633281 @default.
- W3081803629 hasConcept C169760540 @default.
- W3081803629 hasConcept C171056886 @default.
- W3081803629 hasConcept C185592680 @default.
- W3081803629 hasConcept C24998067 @default.
- W3081803629 hasConcept C28328180 @default.
- W3081803629 hasConcept C50738837 @default.
- W3081803629 hasConcept C55493867 @default.
- W3081803629 hasConcept C71924100 @default.
- W3081803629 hasConcept C86803240 @default.
- W3081803629 hasConcept C95444343 @default.
- W3081803629 hasConceptScore W3081803629C104317684 @default.
- W3081803629 hasConceptScore W3081803629C107459253 @default.
- W3081803629 hasConceptScore W3081803629C145103041 @default.
- W3081803629 hasConceptScore W3081803629C1491633281 @default.
- W3081803629 hasConceptScore W3081803629C169760540 @default.
- W3081803629 hasConceptScore W3081803629C171056886 @default.
- W3081803629 hasConceptScore W3081803629C185592680 @default.
- W3081803629 hasConceptScore W3081803629C24998067 @default.
- W3081803629 hasConceptScore W3081803629C28328180 @default.
- W3081803629 hasConceptScore W3081803629C50738837 @default.
- W3081803629 hasConceptScore W3081803629C55493867 @default.
- W3081803629 hasConceptScore W3081803629C71924100 @default.
- W3081803629 hasConceptScore W3081803629C86803240 @default.
- W3081803629 hasConceptScore W3081803629C95444343 @default.
- W3081803629 hasLocation W30818036291 @default.
- W3081803629 hasOpenAccess W3081803629 @default.
- W3081803629 hasPrimaryLocation W30818036291 @default.
- W3081803629 hasRelatedWork W1462465093 @default.
- W3081803629 hasRelatedWork W2005535807 @default.
- W3081803629 hasRelatedWork W2012910100 @default.
- W3081803629 hasRelatedWork W2139272195 @default.
- W3081803629 hasRelatedWork W2344636172 @default.
- W3081803629 hasRelatedWork W2418592407 @default.
- W3081803629 hasRelatedWork W2768952912 @default.
- W3081803629 hasRelatedWork W2896836670 @default.
- W3081803629 hasRelatedWork W3138500615 @default.
- W3081803629 hasRelatedWork W3205902602 @default.
- W3081803629 isParatext "false" @default.
- W3081803629 isRetracted "false" @default.
- W3081803629 magId "3081803629" @default.
- W3081803629 workType "book-chapter" @default.