Matches in SemOpenAlex for { <https://semopenalex.org/work/W3081865700> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3081865700 abstract "Objective Estimate seroprevalence in representative samples from slum and non-slum communities in Mumbai, India, a mega-city in a low or middle-income country and test if prevalence is different in slums. Design After geographically-spaced community sampling of households, one individual per household was tested for IgG antibodies to SARS-CoV-2 N-protein in a two-week interval. Setting Slum and non-slum communities in three wards, one each from the three main zones of Mumbai. Participants Individuals over age 12 who consent to and have no contraindications to venipuncture were eligible. 6,904 participants (4,202 from slums and 2,702 from non-slums) were tested. Main outcome measures The primary outcomes were the positive test rate for IgG antibodies to the SARS-CoV-2 N-protein by demographic group (age and gender) and location (slums and non-slums). The secondary outcome is seroprevalence at slum and non-slum levels. Sera was tested via chemiluminescence (CLIA) using Abbott Diagnostics Architect TM N-protein based test. Seroprevalence was calculated using weights to match the population distribution by age and gender and accounting for imperfect sensitivity and specificity of the test. Results The positive test rate was 54.1% (95% CI: 52.7 to 55.6) and 16.1% (95% CI: 14.9 to 17.4) in slums and non-slums, respectively, a difference of 38 percentage points (P < 0.001). Accounting for imperfect accuracy of tests (e.g., sensitivity, 0.90; specificity 1.00), seroprevalence was as high as 58.4% (95% CI: 56.8 to 59.9) and 17.3% (95% CI: 16 to 18.7) in slums and non-slums, respectively. Conclusions The high seroprevalence in slums implies a moderate infection fatality rate. The stark difference in seroprevalence across slums and non-slums has implications for the efficacy of social distancing, the level of herd immunity, and equity. It underlines the importance of geographic specificity and urban structure in modeling SARS-CoV-2." @default.
- W3081865700 created "2020-09-08" @default.
- W3081865700 creator A5006077219 @default.
- W3081865700 creator A5010932794 @default.
- W3081865700 creator A5018294900 @default.
- W3081865700 creator A5040954758 @default.
- W3081865700 creator A5046781245 @default.
- W3081865700 creator A5049806358 @default.
- W3081865700 creator A5068549566 @default.
- W3081865700 creator A5074154848 @default.
- W3081865700 creator A5076580109 @default.
- W3081865700 creator A5084941944 @default.
- W3081865700 creator A5087299636 @default.
- W3081865700 date "2020-09-01" @default.
- W3081865700 modified "2023-10-02" @default.
- W3081865700 title "Seroprevalence of SARS-CoV-2 in slums and non-slums of Mumbai, India, during June 29-July 19, 2020" @default.
- W3081865700 cites W2271596670 @default.
- W3081865700 cites W2790418319 @default.
- W3081865700 cites W3015281372 @default.
- W3081865700 cites W3021039517 @default.
- W3081865700 cites W3023921501 @default.
- W3081865700 cites W3024982296 @default.
- W3081865700 cites W3036932834 @default.
- W3081865700 cites W3040552450 @default.
- W3081865700 cites W3042990210 @default.
- W3081865700 cites W3047128251 @default.
- W3081865700 cites W4238427425 @default.
- W3081865700 doi "https://doi.org/10.1101/2020.08.27.20182741" @default.
- W3081865700 hasPublicationYear "2020" @default.
- W3081865700 type Work @default.
- W3081865700 sameAs 3081865700 @default.
- W3081865700 citedByCount "26" @default.
- W3081865700 countsByYear W30818657002020 @default.
- W3081865700 countsByYear W30818657002021 @default.
- W3081865700 countsByYear W30818657002022 @default.
- W3081865700 countsByYear W30818657002023 @default.
- W3081865700 crossrefType "posted-content" @default.
- W3081865700 hasAuthorship W3081865700A5006077219 @default.
- W3081865700 hasAuthorship W3081865700A5010932794 @default.
- W3081865700 hasAuthorship W3081865700A5018294900 @default.
- W3081865700 hasAuthorship W3081865700A5040954758 @default.
- W3081865700 hasAuthorship W3081865700A5046781245 @default.
- W3081865700 hasAuthorship W3081865700A5049806358 @default.
- W3081865700 hasAuthorship W3081865700A5068549566 @default.
- W3081865700 hasAuthorship W3081865700A5074154848 @default.
- W3081865700 hasAuthorship W3081865700A5076580109 @default.
- W3081865700 hasAuthorship W3081865700A5084941944 @default.
- W3081865700 hasAuthorship W3081865700A5087299636 @default.
- W3081865700 hasBestOaLocation W30818657001 @default.
- W3081865700 hasConcept C126322002 @default.
- W3081865700 hasConcept C144024400 @default.
- W3081865700 hasConcept C149923435 @default.
- W3081865700 hasConcept C159654299 @default.
- W3081865700 hasConcept C203014093 @default.
- W3081865700 hasConcept C205649164 @default.
- W3081865700 hasConcept C2778494684 @default.
- W3081865700 hasConcept C2778631157 @default.
- W3081865700 hasConcept C2908647359 @default.
- W3081865700 hasConcept C44249647 @default.
- W3081865700 hasConcept C45189115 @default.
- W3081865700 hasConcept C71924100 @default.
- W3081865700 hasConcept C99454951 @default.
- W3081865700 hasConceptScore W3081865700C126322002 @default.
- W3081865700 hasConceptScore W3081865700C144024400 @default.
- W3081865700 hasConceptScore W3081865700C149923435 @default.
- W3081865700 hasConceptScore W3081865700C159654299 @default.
- W3081865700 hasConceptScore W3081865700C203014093 @default.
- W3081865700 hasConceptScore W3081865700C205649164 @default.
- W3081865700 hasConceptScore W3081865700C2778494684 @default.
- W3081865700 hasConceptScore W3081865700C2778631157 @default.
- W3081865700 hasConceptScore W3081865700C2908647359 @default.
- W3081865700 hasConceptScore W3081865700C44249647 @default.
- W3081865700 hasConceptScore W3081865700C45189115 @default.
- W3081865700 hasConceptScore W3081865700C71924100 @default.
- W3081865700 hasConceptScore W3081865700C99454951 @default.
- W3081865700 hasLocation W30818657001 @default.
- W3081865700 hasOpenAccess W3081865700 @default.
- W3081865700 hasPrimaryLocation W30818657001 @default.
- W3081865700 hasRelatedWork W2016667107 @default.
- W3081865700 hasRelatedWork W2338214064 @default.
- W3081865700 hasRelatedWork W2748952813 @default.
- W3081865700 hasRelatedWork W2899084033 @default.
- W3081865700 hasRelatedWork W3081865700 @default.
- W3081865700 hasRelatedWork W3148169289 @default.
- W3081865700 hasRelatedWork W3165971069 @default.
- W3081865700 hasRelatedWork W39432111 @default.
- W3081865700 hasRelatedWork W2188364749 @default.
- W3081865700 hasRelatedWork W2621083335 @default.
- W3081865700 isParatext "false" @default.
- W3081865700 isRetracted "false" @default.
- W3081865700 magId "3081865700" @default.
- W3081865700 workType "article" @default.