Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082086937> ?p ?o ?g. }
- W3082086937 endingPage "e0238188" @default.
- W3082086937 startingPage "e0238188" @default.
- W3082086937 abstract "Visceral leishmaniasis caused by the protozoan Leishmania infantum is a zoonosis. The domestic dog is the primary reservoir in urban areas. This study aimed to evaluate the frequency, active infection and load of L. infantum in the genital tract of male and female dogs seropositive for this parasite, as well as to identify histological genital alterations associated with this protozoan. We studied 45 male and 25 female L. infantum-seropositive noncastrated dogs from the same endemic area in Brazil. Tissue samples from the testis, epididymis, prostate, vulva, vagina, and uterus were examined by singleplex qPCR and parasitological tests (histopathology, immunohistochemistry, and parasitological culture). The latter were performed for the detection of active infection (parasites able to multiply and to induce lesions). Forty-four (98%) males and 25 (100%) females were positive for L. infantum in the genital tract (epididymis: 98%; vulva: 92%; vagina: 92%; testis: 91%; uterus: 84%; prostate: 66%). Active infection in the genital tract was confirmed in 69% of males and 64% of females (32% in the uterus). Parasite loads were similar in the testis, vulva, epididymis and vagina and lower in the prostate. Only the parasite load in the vagina was significantly associated with the number of clinical signs. Granulomatous inflammation predominated in all organs, except for the prostate. Only in the testis and epididymis was the inflammatory infiltrate significantly more intense among dogs with a higher parasite load in these organs. The high frequency, detection of active infection and similarity of L. infantum loads in the genital tract of infected males and females suggest the potential of venereal transmission of this parasite by both sexes and of vertical transmission by females in the area studied. Additionally, vertical transmission may be frequent since active L. infantum infection was a common observation in the uterus." @default.
- W3082086937 created "2020-09-08" @default.
- W3082086937 creator A5009746035 @default.
- W3082086937 creator A5024202243 @default.
- W3082086937 creator A5030755267 @default.
- W3082086937 creator A5031179098 @default.
- W3082086937 creator A5039023178 @default.
- W3082086937 creator A5042035313 @default.
- W3082086937 creator A5056201392 @default.
- W3082086937 creator A5061759897 @default.
- W3082086937 creator A5071832571 @default.
- W3082086937 creator A5071906213 @default.
- W3082086937 creator A5079863378 @default.
- W3082086937 creator A5080075208 @default.
- W3082086937 creator A5079045104 @default.
- W3082086937 date "2020-09-01" @default.
- W3082086937 modified "2023-09-26" @default.
- W3082086937 title "Frequency, active infection and load of Leishmania infantum and associated histological alterations in the genital tract of male and female dogs" @default.
- W3082086937 cites W1599478211 @default.
- W3082086937 cites W1971497195 @default.
- W3082086937 cites W1996131067 @default.
- W3082086937 cites W2002332347 @default.
- W3082086937 cites W2002666026 @default.
- W3082086937 cites W2010504683 @default.
- W3082086937 cites W2019753167 @default.
- W3082086937 cites W2040452570 @default.
- W3082086937 cites W2051012840 @default.
- W3082086937 cites W2059990662 @default.
- W3082086937 cites W2060446084 @default.
- W3082086937 cites W2064937136 @default.
- W3082086937 cites W2077700823 @default.
- W3082086937 cites W2081031236 @default.
- W3082086937 cites W2089190207 @default.
- W3082086937 cites W2095737595 @default.
- W3082086937 cites W2098583665 @default.
- W3082086937 cites W2105673140 @default.
- W3082086937 cites W2117812048 @default.
- W3082086937 cites W2140355394 @default.
- W3082086937 cites W2155215879 @default.
- W3082086937 cites W2164777277 @default.
- W3082086937 cites W2166555157 @default.
- W3082086937 cites W2170563859 @default.
- W3082086937 cites W2185665142 @default.
- W3082086937 cites W2282261954 @default.
- W3082086937 cites W2289361258 @default.
- W3082086937 cites W2299973350 @default.
- W3082086937 cites W2345342392 @default.
- W3082086937 cites W2402675389 @default.
- W3082086937 cites W2501761834 @default.
- W3082086937 cites W2519340404 @default.
- W3082086937 cites W2584290187 @default.
- W3082086937 cites W2607126692 @default.
- W3082086937 cites W2728056758 @default.
- W3082086937 cites W2745341171 @default.
- W3082086937 cites W2804488909 @default.
- W3082086937 cites W2912374006 @default.
- W3082086937 cites W2970269070 @default.
- W3082086937 cites W76674196 @default.
- W3082086937 cites W2037122865 @default.
- W3082086937 doi "https://doi.org/10.1371/journal.pone.0238188" @default.
- W3082086937 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7462300" @default.
- W3082086937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32870947" @default.
- W3082086937 hasPublicationYear "2020" @default.
- W3082086937 type Work @default.
- W3082086937 sameAs 3082086937 @default.
- W3082086937 citedByCount "6" @default.
- W3082086937 countsByYear W30820869372021 @default.
- W3082086937 countsByYear W30820869372022 @default.
- W3082086937 countsByYear W30820869372023 @default.
- W3082086937 crossrefType "journal-article" @default.
- W3082086937 hasAuthorship W3082086937A5009746035 @default.
- W3082086937 hasAuthorship W3082086937A5024202243 @default.
- W3082086937 hasAuthorship W3082086937A5030755267 @default.
- W3082086937 hasAuthorship W3082086937A5031179098 @default.
- W3082086937 hasAuthorship W3082086937A5039023178 @default.
- W3082086937 hasAuthorship W3082086937A5042035313 @default.
- W3082086937 hasAuthorship W3082086937A5056201392 @default.
- W3082086937 hasAuthorship W3082086937A5061759897 @default.
- W3082086937 hasAuthorship W3082086937A5071832571 @default.
- W3082086937 hasAuthorship W3082086937A5071906213 @default.
- W3082086937 hasAuthorship W3082086937A5079045104 @default.
- W3082086937 hasAuthorship W3082086937A5079863378 @default.
- W3082086937 hasAuthorship W3082086937A5080075208 @default.
- W3082086937 hasBestOaLocation W30820869371 @default.
- W3082086937 hasConcept C105702510 @default.
- W3082086937 hasConcept C134018914 @default.
- W3082086937 hasConcept C142724271 @default.
- W3082086937 hasConcept C183021626 @default.
- W3082086937 hasConcept C203014093 @default.
- W3082086937 hasConcept C2775846227 @default.
- W3082086937 hasConcept C2776316342 @default.
- W3082086937 hasConcept C2776555147 @default.
- W3082086937 hasConcept C2777744392 @default.
- W3082086937 hasConcept C2778689377 @default.
- W3082086937 hasConcept C2779066055 @default.
- W3082086937 hasConcept C2779234561 @default.
- W3082086937 hasConcept C2781087480 @default.
- W3082086937 hasConcept C2781254305 @default.