FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082201801> ?p ?o ?g. }

• W3082201801 endingPage "233" @default.
• W3082201801 startingPage "233" @default.
• W3082201801 abstract "A desirable attribute of novel antimicrobial agents for bacterial diarrhea is decreased toxicity toward host intestinal microbiota. In addition, gut dysbiosis is associated with an increased risk of developing intestinal cancer. In this study, the selective growth-inhibitory activities of ten phytochemicals and their synthetic analogs (berberine, bismuth subsalicylate, ferron, 8-hydroxyquinoline, chloroxine, nitroxoline, salicylic acid, sanguinarine, tannic acid, and zinc pyrithione), as well as those of six commercial antibiotics (ceftriaxone, ciprofloxacin, chloramphenicol, metronidazole, tetracycline, and vancomycin) against 21 intestinal pathogenic/probiotic (e.g., Salmonella spp. and bifidobacteria) bacterial strains and three intestinal cancer/normal (Caco-2, HT29, and FHs 74 Int) cell lines were examined in vitro using the broth microdilution method and thiazolyl blue tetrazolium bromide assay. Chloroxine, ciprofloxacin, nitroxoline, tetracycline, and zinc pyrithione exhibited the most potent selective growth-inhibitory activity against pathogens, whereas 8-hydroxyquinoline, chloroxine, nitroxoline, sanguinarine, and zinc pyrithione exhibited the highest cytotoxic activity against cancer cells. None of the tested antibiotics were cytotoxic to normal cells, whereas 8-hydroxyquinoline and sanguinarine exhibited selective antiproliferative activity against cancer cells. These findings indicate that 8-hydroxyquinoline alkaloids and metal-pyridine derivative complexes are chemical structures derived from plants with potential bioactive properties in terms of selective antibacterial and anticancer activities against diarrheagenic bacteria and intestinal cancer cells." @default.
• W3082201801 created "2020-09-08" @default.
• W3082201801 creator A5026932680 @default.
• W3082201801 creator A5055314121 @default.
• W3082201801 creator A5062953329 @default.
• W3082201801 creator A5067443937 @default.
• W3082201801 creator A5070181393 @default.
• W3082201801 creator A5090547269 @default.
• W3082201801 date "2020-09-03" @default.
• W3082201801 modified "2023-10-14" @default.
• W3082201801 title "In Vitro Selective Growth-Inhibitory Activities of Phytochemicals, Synthetic Phytochemical Analogs, and Antibiotics against Diarrheagenic/Probiotic Bacteria and Cancer/Normal Intestinal Cells" @default.
• W3082201801 cites W1567299727 @default.
• W3082201801 cites W1828039188 @default.
• W3082201801 cites W1998760904 @default.
• W3082201801 cites W2000947452 @default.
• W3082201801 cites W2007291733 @default.
• W3082201801 cites W2012450584 @default.
• W3082201801 cites W2029609560 @default.
• W3082201801 cites W2052997955 @default.
• W3082201801 cites W2053204557 @default.
• W3082201801 cites W2076029682 @default.
• W3082201801 cites W207915311 @default.
• W3082201801 cites W2080276670 @default.
• W3082201801 cites W2089338647 @default.
• W3082201801 cites W2090476113 @default.
• W3082201801 cites W2098250301 @default.
• W3082201801 cites W2109201263 @default.
• W3082201801 cites W2114918609 @default.
• W3082201801 cites W2122749943 @default.
• W3082201801 cites W2124205716 @default.
• W3082201801 cites W2126142688 @default.
• W3082201801 cites W2132485408 @default.
• W3082201801 cites W2145147747 @default.
• W3082201801 cites W2146523057 @default.
• W3082201801 cites W2195938011 @default.
• W3082201801 cites W2291434428 @default.
• W3082201801 cites W2319419010 @default.
• W3082201801 cites W2346482083 @default.
• W3082201801 cites W2409497273 @default.
• W3082201801 cites W2410831748 @default.
• W3082201801 cites W2419535666 @default.
• W3082201801 cites W2545538486 @default.
• W3082201801 cites W2560656267 @default.
• W3082201801 cites W2571057078 @default.
• W3082201801 cites W2591325925 @default.
• W3082201801 cites W2684823302 @default.
• W3082201801 cites W2765712927 @default.
• W3082201801 cites W2772457361 @default.
• W3082201801 cites W2818339756 @default.
• W3082201801 cites W2885831009 @default.
• W3082201801 cites W2891391648 @default.
• W3082201801 cites W2952200067 @default.
• W3082201801 cites W2965568488 @default.
• W3082201801 cites W3010165740 @default.
• W3082201801 cites W3011988355 @default.
• W3082201801 cites W3034499883 @default.
• W3082201801 doi "https://doi.org/10.3390/ph13090233" @default.
• W3082201801 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7558399" @default.
• W3082201801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32899218" @default.
• W3082201801 hasPublicationYear "2020" @default.
• W3082201801 type Work @default.
• W3082201801 sameAs 3082201801 @default.
• W3082201801 citedByCount "13" @default.
• W3082201801 countsByYear W30822018012021 @default.
• W3082201801 countsByYear W30822018012022 @default.
• W3082201801 countsByYear W30822018012023 @default.
• W3082201801 crossrefType "journal-article" @default.
• W3082201801 hasAuthorship W3082201801A5026932680 @default.
• W3082201801 hasAuthorship W3082201801A5055314121 @default.
• W3082201801 hasAuthorship W3082201801A5062953329 @default.
• W3082201801 hasAuthorship W3082201801A5067443937 @default.
• W3082201801 hasAuthorship W3082201801A5070181393 @default.
• W3082201801 hasAuthorship W3082201801A5090547269 @default.
• W3082201801 hasBestOaLocation W30822018011 @default.
• W3082201801 hasConcept C185592680 @default.
• W3082201801 hasConcept C2778512257 @default.
• W3082201801 hasConcept C2778883795 @default.
• W3082201801 hasConcept C2780104969 @default.
• W3082201801 hasConcept C2780255968 @default.
• W3082201801 hasConcept C4937899 @default.
• W3082201801 hasConcept C501593827 @default.
• W3082201801 hasConcept C523546767 @default.
• W3082201801 hasConcept C54355233 @default.
• W3082201801 hasConcept C86803240 @default.
• W3082201801 hasConcept C89423630 @default.
• W3082201801 hasConcept C98274493 @default.
• W3082201801 hasConceptScore W3082201801C185592680 @default.
• W3082201801 hasConceptScore W3082201801C2778512257 @default.
• W3082201801 hasConceptScore W3082201801C2778883795 @default.
• W3082201801 hasConceptScore W3082201801C2780104969 @default.
• W3082201801 hasConceptScore W3082201801C2780255968 @default.
• W3082201801 hasConceptScore W3082201801C4937899 @default.
• W3082201801 hasConceptScore W3082201801C501593827 @default.
• W3082201801 hasConceptScore W3082201801C523546767 @default.
• W3082201801 hasConceptScore W3082201801C54355233 @default.
• W3082201801 hasConceptScore W3082201801C86803240 @default.
• W3082201801 hasConceptScore W3082201801C89423630 @default.
• W3082201801 hasConceptScore W3082201801C98274493 @default.

• next