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- W3082335232 endingPage "111341" @default.
- W3082335232 startingPage "111341" @default.
- W3082335232 abstract "The objective of the work was to improve the intestinal stability and pH sensitive release of quercetin in the gastrointestinal tract. To achieve this aim, novel quercetin loaded pH sensitive hydrogel beads of gellan gum were developed through an ionic cross-linking technique using calcium chloride (CaCl2) as cross-linking agents. Field emission scanning electron microscopy (FESEM) was used to characterize the morphological appearance of the prepared hydrogel beads. Drug-polymer and drug-CaCl2 interaction were studied by using infrared spectroscopy. The important finding of the study was the formation of stable hydrogel beads at a very low concentration of CaCl2 (0.3 % w/v). There was a drug polymer interaction in addition to polymer and CaCl2 interaction that is confirmed by infrared spectroscopy. All the formulation shows good entrapment efficiencies within the range of 58.56–93.71 %. The prepared beads exhibited a pH responsive swelling behavior with maximum swelling at the simulated intestinal fluid (pH 7.4) (SIF). Hydrogel beads also showed a pH responsive release behavior and sustained release of drug at SIF. Moreover, the intestinal stability of quercetin was improved when encapsulated in gellan gum hydrogel beads in comparison to the solution containing quercetin." @default.
- W3082335232 created "2020-09-08" @default.
- W3082335232 creator A5036638461 @default.
- W3082335232 creator A5049940690 @default.
- W3082335232 creator A5068727523 @default.
- W3082335232 date "2020-12-01" @default.
- W3082335232 modified "2023-10-13" @default.
- W3082335232 title "Enhanced intestinal stability and pH sensitive release of quercetin in GIT through gellan gum hydrogels" @default.
- W3082335232 cites W1010530109 @default.
- W3082335232 cites W1597509158 @default.
- W3082335232 cites W1923009415 @default.
- W3082335232 cites W1968988805 @default.
- W3082335232 cites W1969083496 @default.
- W3082335232 cites W1971120211 @default.
- W3082335232 cites W1971127546 @default.
- W3082335232 cites W1971847221 @default.
- W3082335232 cites W1975160666 @default.
- W3082335232 cites W1980866515 @default.
- W3082335232 cites W1985605738 @default.
- W3082335232 cites W1985841452 @default.
- W3082335232 cites W1986367116 @default.
- W3082335232 cites W1990963835 @default.
- W3082335232 cites W1991968794 @default.
- W3082335232 cites W1993804396 @default.
- W3082335232 cites W1995785958 @default.
- W3082335232 cites W1996745979 @default.
- W3082335232 cites W2001784275 @default.
- W3082335232 cites W2003566226 @default.
- W3082335232 cites W2003620214 @default.
- W3082335232 cites W2003987803 @default.
- W3082335232 cites W2007068681 @default.
- W3082335232 cites W2013245568 @default.
- W3082335232 cites W2016829041 @default.
- W3082335232 cites W2020473652 @default.
- W3082335232 cites W2021978496 @default.
- W3082335232 cites W2023056191 @default.
- W3082335232 cites W2024215200 @default.
- W3082335232 cites W2024344003 @default.
- W3082335232 cites W2028082266 @default.
- W3082335232 cites W2028412605 @default.
- W3082335232 cites W2029376729 @default.
- W3082335232 cites W2029738042 @default.
- W3082335232 cites W2030821888 @default.
- W3082335232 cites W2039776043 @default.
- W3082335232 cites W2044264387 @default.
- W3082335232 cites W2047271327 @default.
- W3082335232 cites W2048259151 @default.
- W3082335232 cites W2049335486 @default.
- W3082335232 cites W2054632770 @default.
- W3082335232 cites W2054818081 @default.
- W3082335232 cites W2063549798 @default.
- W3082335232 cites W2067189454 @default.
- W3082335232 cites W2074169655 @default.
- W3082335232 cites W2094726594 @default.
- W3082335232 cites W2095588336 @default.
- W3082335232 cites W2102042241 @default.
- W3082335232 cites W2110561122 @default.
- W3082335232 cites W2121868928 @default.
- W3082335232 cites W2122320945 @default.
- W3082335232 cites W2131557988 @default.
- W3082335232 cites W2133019478 @default.
- W3082335232 cites W2137153753 @default.
- W3082335232 cites W2142596415 @default.
- W3082335232 cites W2142802606 @default.
- W3082335232 cites W2147304506 @default.
- W3082335232 cites W2152792277 @default.
- W3082335232 cites W2160845923 @default.
- W3082335232 cites W2165774785 @default.
- W3082335232 cites W2169035197 @default.
- W3082335232 cites W2212958353 @default.
- W3082335232 cites W2277270128 @default.
- W3082335232 cites W2340603164 @default.
- W3082335232 cites W2511965550 @default.
- W3082335232 cites W2513976454 @default.
- W3082335232 cites W2519809863 @default.
- W3082335232 cites W2527943384 @default.
- W3082335232 cites W2539107597 @default.
- W3082335232 cites W2593071454 @default.
- W3082335232 cites W2608577469 @default.
- W3082335232 cites W2611809255 @default.
- W3082335232 cites W2767451026 @default.
- W3082335232 cites W2767678605 @default.
- W3082335232 cites W2785930119 @default.
- W3082335232 cites W2792677079 @default.
- W3082335232 cites W2793574922 @default.
- W3082335232 cites W2832419573 @default.
- W3082335232 cites W2890388654 @default.
- W3082335232 cites W2911180762 @default.
- W3082335232 cites W2914970013 @default.
- W3082335232 cites W2915040338 @default.
- W3082335232 cites W359508033 @default.
- W3082335232 doi "https://doi.org/10.1016/j.colsurfb.2020.111341" @default.
- W3082335232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32916438" @default.
- W3082335232 hasPublicationYear "2020" @default.
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