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• W3082376229 abstract "Klinefelter syndrome (KS), characterized by the presence of one extra X-chromosome in the male karyotype, is the most frequent chromosomal abnormality in males worldwide. KS is characterized by variable symptoms, with infertility as the main clinical sign. Despite the large prevalence of this condition in the population, the molecular basis for the phenotypic traits in KS has not been fully elucidated yet. In this chapter, we will review the most recent data provided by scientific literature with specific attention to the mechanisms leading to testis dysfunction in KS patients. The opportunities and the challenges related to the application of assisted reproductive technology (ART) protocols in KS patients will also be discussed." @default.
• W3082376229 created "2020-09-08" @default.
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• W3082376229 date "2020-01-01" @default.
• W3082376229 modified "2023-09-26" @default.
• W3082376229 title "Genetic of Gametes" @default.
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• W3082376229 doi "https://doi.org/10.1007/978-3-030-51410-5_13" @default.
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