Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082385008> ?p ?o ?g. }
- W3082385008 endingPage "1319" @default.
- W3082385008 startingPage "1319" @default.
- W3082385008 abstract "In the Aspergillus species, conidia are asexual spores that are infectious particles responsible for propagation. Conidia contain various mycotoxins that can have detrimental effects in humans. Previous study demonstrated that VadA is required for fungal development and spore viability in the model fungus Aspergillus nidulans. In the present study, vadA transcriptomic analysis revealed that VadA affects the mRNA expression of a variety of genes in A. nidulans conidia. The genes that were primarily affected in conidia were associated with trehalose biosynthesis, cell-wall integrity, stress response, and secondary metabolism. Genetic changes caused by deletion of vadA were related to phenotypes of the vadA deletion mutant conidia. The deletion of vadA resulted in increased conidial sensitivity against ultraviolet stress and induced germ tube formation in the presence and absence of glucose. In addition, most genes in the secondary metabolism gene clusters of sterigmatocystin, asperfuranone, monodictyphenone, and asperthecin were upregulated in the mutant conidia with vadA deletion. The deletion of vadA led to an increase in the amount of sterigmatocystin in the conidia, suggesting that VadA is essential for the repression of sterigmatocystin production in conidia. These results suggest that VadA coordinates conidia maturation, stress response, and secondary metabolism in A. nidulans conidia." @default.
- W3082385008 created "2020-09-08" @default.
- W3082385008 creator A5088592256 @default.
- W3082385008 creator A5090627749 @default.
- W3082385008 date "2020-08-30" @default.
- W3082385008 modified "2023-09-30" @default.
- W3082385008 title "Genome Wide Analysis Reveals the Role of VadA in Stress Response, Germination, and Sterigmatocystin Production in Aspergillus nidulans Conidia" @default.
- W3082385008 cites W1965369408 @default.
- W3082385008 cites W1968929892 @default.
- W3082385008 cites W1989023864 @default.
- W3082385008 cites W1989725886 @default.
- W3082385008 cites W1990326485 @default.
- W3082385008 cites W1997710299 @default.
- W3082385008 cites W2001057820 @default.
- W3082385008 cites W2006475796 @default.
- W3082385008 cites W2022680565 @default.
- W3082385008 cites W2031398937 @default.
- W3082385008 cites W2045444560 @default.
- W3082385008 cites W2058501576 @default.
- W3082385008 cites W2085683856 @default.
- W3082385008 cites W2103017472 @default.
- W3082385008 cites W2125533723 @default.
- W3082385008 cites W2125632841 @default.
- W3082385008 cites W2130963153 @default.
- W3082385008 cites W2134526812 @default.
- W3082385008 cites W2141458291 @default.
- W3082385008 cites W2153911335 @default.
- W3082385008 cites W2169456326 @default.
- W3082385008 cites W2169784081 @default.
- W3082385008 cites W2254284735 @default.
- W3082385008 cites W2345429004 @default.
- W3082385008 cites W2351917348 @default.
- W3082385008 cites W2436737319 @default.
- W3082385008 cites W2443945899 @default.
- W3082385008 cites W2570759065 @default.
- W3082385008 cites W2588882259 @default.
- W3082385008 cites W2605030089 @default.
- W3082385008 cites W2612122574 @default.
- W3082385008 cites W2614664430 @default.
- W3082385008 cites W2642015672 @default.
- W3082385008 cites W2729187101 @default.
- W3082385008 cites W2761946910 @default.
- W3082385008 cites W2886588929 @default.
- W3082385008 cites W2888160344 @default.
- W3082385008 cites W2897873206 @default.
- W3082385008 cites W2901069854 @default.
- W3082385008 cites W2918101278 @default.
- W3082385008 cites W2979828873 @default.
- W3082385008 cites W2992613658 @default.
- W3082385008 cites W2999664232 @default.
- W3082385008 cites W3000271066 @default.
- W3082385008 cites W3006353275 @default.
- W3082385008 cites W3039769650 @default.
- W3082385008 cites W4230203434 @default.
- W3082385008 doi "https://doi.org/10.3390/microorganisms8091319" @default.
- W3082385008 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7565415" @default.
- W3082385008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32872591" @default.
- W3082385008 hasPublicationYear "2020" @default.
- W3082385008 type Work @default.
- W3082385008 sameAs 3082385008 @default.
- W3082385008 citedByCount "8" @default.
- W3082385008 countsByYear W30823850082021 @default.
- W3082385008 countsByYear W30823850082022 @default.
- W3082385008 countsByYear W30823850082023 @default.
- W3082385008 crossrefType "journal-article" @default.
- W3082385008 hasAuthorship W3082385008A5088592256 @default.
- W3082385008 hasAuthorship W3082385008A5090627749 @default.
- W3082385008 hasBestOaLocation W30823850081 @default.
- W3082385008 hasConcept C104317684 @default.
- W3082385008 hasConcept C143065580 @default.
- W3082385008 hasConcept C174618031 @default.
- W3082385008 hasConcept C2776923806 @default.
- W3082385008 hasConcept C2777922716 @default.
- W3082385008 hasConcept C43143990 @default.
- W3082385008 hasConcept C55493867 @default.
- W3082385008 hasConcept C59822182 @default.
- W3082385008 hasConcept C84699730 @default.
- W3082385008 hasConcept C86803240 @default.
- W3082385008 hasConcept C89423630 @default.
- W3082385008 hasConceptScore W3082385008C104317684 @default.
- W3082385008 hasConceptScore W3082385008C143065580 @default.
- W3082385008 hasConceptScore W3082385008C174618031 @default.
- W3082385008 hasConceptScore W3082385008C2776923806 @default.
- W3082385008 hasConceptScore W3082385008C2777922716 @default.
- W3082385008 hasConceptScore W3082385008C43143990 @default.
- W3082385008 hasConceptScore W3082385008C55493867 @default.
- W3082385008 hasConceptScore W3082385008C59822182 @default.
- W3082385008 hasConceptScore W3082385008C84699730 @default.
- W3082385008 hasConceptScore W3082385008C86803240 @default.
- W3082385008 hasConceptScore W3082385008C89423630 @default.
- W3082385008 hasFunder F4320322120 @default.
- W3082385008 hasIssue "9" @default.
- W3082385008 hasLocation W30823850081 @default.
- W3082385008 hasLocation W30823850082 @default.
- W3082385008 hasLocation W30823850083 @default.
- W3082385008 hasLocation W30823850084 @default.
- W3082385008 hasOpenAccess W3082385008 @default.
- W3082385008 hasPrimaryLocation W30823850081 @default.